PTPRA 抗体 (C-Term)
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- 抗原 See all PTPRA 抗体
- PTPRA (Protein tyrosine Phosphatase, Receptor Type, A (PTPRA))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 兔, 斑马鱼, 马, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTPRA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SRQIRQFHFH GWPEVGIPSD GKGMISIIAA VQKQQQQSGN HPITVHCSAG
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PTPRA. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PTPRA
- Top Product
- Discover our top product PTPRA Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 802 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PTPRA (Protein tyrosine Phosphatase, Receptor Type, A (PTPRA))
- 别名
- PTPRA (PTPRA 产品)
- 别名
- PTPRA antibody, heptp antibody, hlpr antibody, hptpa antibody, hptpalpha antibody, lrp antibody, ptpa antibody, ptprl2 antibody, r-ptp-alpha antibody, rptpa antibody, HEPTP antibody, HLPR antibody, HPTPA antibody, HPTPalpha antibody, LRP antibody, PTPA antibody, PTPRL2 antibody, R-PTP-alpha antibody, RPTPA antibody, Ptpa antibody, Ptpalpha antibody, Rptpalpha antibody, Rptra antibody, Rptralpha antibody, RPTP[a] antibody, zf-RPTP[a] antibody, ptpa-a antibody, protein tyrosine phosphatase, receptor type A antibody, protein tyrosine phosphatase, receptor type, A antibody, protein tyrosine phosphatase, receptor type A S homeolog antibody, PTPRA antibody, ptpra antibody, Ptpra antibody, ptpra.S antibody
- 背景
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PTPRA is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRA contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. PTPRA has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.
Alias Symbols: HEPTP, HLPR, HPTPA, HPTPalpha, LRP, PTPA, PTPRL2, R-PTP-alpha, RPTPA
Protein Interaction Partner: UBC, GRB2, CALM1, GABARAPL2, UVRAG, BCAR1, PTPRD, PTPRS, SRC, PTPRF, PRKCD, PTPRM, PTPRA, KCNA2, FYN,
Protein Size: 802 - 分子量
- 89 kDa
- 基因ID
- 5786
- NCBI登录号
- NM_002836, NP_002827
- UniProt
- P18433
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