HGF 抗体 (Middle Region)
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- 抗原 See all HGF 抗体
- HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 小鼠, 犬, 兔, Cow, 马, 豚鼠, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HGF antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- NENYCRNPDD DAHGPWCYTG NPLIPWDYCP ISRCEGDTTP TIVNLDHPVI
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against HGF. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human HGF
- Top Product
- Discover our top product HGF Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 728 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
- 别名
- HGF (HGF 产品)
- 别名
- DFNB39 antibody, F-TCF antibody, HGFB antibody, HPTA antibody, SF antibody, HGF antibody, C230052L06Rik antibody, HGF/SF antibody, NK1 antibody, NK2 antibody, SF/HGF antibody, hepatocyte growth factor antibody, HGF antibody, Hgf antibody
- 背景
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Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69- kDa alpha-chain and 34- kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity.
Alias Symbols: F-TCF, HGFB, HPTA, SF, DFNB39
Protein Interaction Partner: ADAMTSL4, MEOX2, MET, F11, ST14, HGFAC, LCN2, KLKB1, VTN, PLAU, CLEC3B, SDC1, SDC2, HPN, HGF, FN1, NRP1,
Protein Size: 728 - 分子量
- 83 kDa
- 基因ID
- 3082
- NCBI登录号
- NM_001010932, NP_001010932
- UniProt
- P14210
- 途径
- RTK signaling, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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