Solute Carrier Family 25 (Mitochondrial Carrier, Oxoglutarate Carrier), Member 11 (SLC25A11) (N-Term) 抗体

ABIN2781591 产品详细信息, 供应商: Log in to see
抗原
  • SLC25A11
  • 2310022P18Rik
  • 2oxoc
  • fa07h09
  • wu:fa07h09
  • zgc:86898
  • OGC
  • SLC20A4
  • solute carrier family 25 member 11
  • solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11
  • solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
  • solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 L homeolog
  • SLC25A11
  • Slc25a11
  • slc25a11
  • slc25a11.L
抗原表位
N-Term
10
5
4
3
3
2
2
2
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠, 绵羊, 斑马鱼
57
38
37
3
3
3
3
3
3
3
2
2
2
1
1
宿主

45
12
克隆类型
多克隆
标记
非结合性
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Western Blotting (WB)
40
21
16
13
10
选项
Supplier
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Supplier Product No.
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免疫原 The immunogen is a synthetic peptide directed towards the N terminal region of human SLC25A11
Blocking Peptide Blocking peptide for this product available: ABIN983887
序列 AATASAGAGG IDGKPRTSPK SVKFLFGGLA GMGATVFVQP LDLVKNRMQL
预测反应 Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 85%
产品特性 This is a rabbit polyclonal antibody against SLC25A11. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
别名 SLC25A11 (SLC25A11 Antibody 摘要)
背景 SLC25A11 catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.
Alias Symbols: OGC, SLC20A4
Protein Interaction Partner: RAPGEF2, UBC, SUMO2, STAU1, SUZ12, RNF2, BMI1, FBXO6, FBXO46, FBXW4, ADRB2, CLN5, CLN3, MMS19, UBL4A, MDC1, ECT2, FLOT1, HDAC5, MYC, ICT1, CEBPA, CAMKK2, BABAM1, SLC25A11, COPA, CDKN1A,
Protein Size: 314
分子量 34 kDa
基因ID 8402
NCBI登录号 NM_003562, NP_003553
UniProt Q02978
途径 Dicarboxylic Acid Transport
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 314 AA

限制 仅限研究用
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
厂商提供的图像
Western Blotting (WB) image for anti-Solute Carrier Family 25 (Mitochondrial Carrier, Oxoglutarate Carrier), Member 11 (SLC25A11) (N-Term) antibody (ABIN2781591) WB Suggested Anti-SLC25A11 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
背景 Kabe, Ohmori, Shinouchi, Tsuboi, Hirao, Azuma, Watanabe, Okura, Handa: "Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier." in: The Journal of biological chemistry, Vol. 281, Issue 42, pp. 31729-35, 2006 (PubMed).

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