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NR2E3 抗体 (N-Term)

NR2E3 适用: 人, 小鼠, 大鼠, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780915
发货至: 中国
  • 抗原 See all NR2E3 抗体
    NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 59
    • 14
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, Pig
    宿主
    • 56
    • 3
    克隆类型
    • 57
    • 2
    多克隆
    标记
    • 24
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NR2E3 antibody is un-conjugated
    应用范围
    • 43
    • 23
    • 13
    • 13
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    METRPTALMS STVAAAAPAA GAASRKESPG RWGLGEDPTG VSPSLQCRVC
    预测反应
    Cow: 86%, Human: 100%, Mouse: 93%, Pig: 79%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against NR2E3. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human NR2E3
    Top Product
    Discover our top product NR2E3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 410 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hayashi, Gekka, Goto-Omoto, Takeuchi, Kubo, Kitahara: "Novel NR2E3 mutations (R104Q, R334G) associated with a mild form of enhanced S-cone syndrome demonstrate compound heterozygosity." in: Ophthalmology, Vol. 112, Issue 12, pp. 2115, (2005) (PubMed).

  • 抗原
    NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))
    别名
    NR2E3 (NR2E3 产品)
    别名
    ESCS antibody, PNR antibody, RNR antibody, RP37 antibody, rd7 antibody, LOC100228348 antibody, A930035N01Rik antibody, wu:fj55b07 antibody, zgc:103631 antibody, nuclear receptor subfamily 2 group E member 3 antibody, nuclear receptor subfamily 2, group E, member 3 antibody, NR2E3 antibody, Nr2e3 antibody, nr2e3 antibody
    背景
    NR2E3 is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. NR2E3 is a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome.This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Alias Symbols: PNR, RNR, rd7, ESCS, RP37
    Protein Interaction Partner: BCL11A, SIN3A, DHX30, TBL3, MYBBP1A, NCOR1, HDAC3, RBL1, RBBP7, RBBP4, HDAC1, CDK9, VDR, DEDD2, RBFOX2, IRF9, ZNF232, SNAPC1, PPARG, HOXC13, NR3C1, ELAVL2, POLR3D, RARA, NR1D1, CRX, RXRB, RXRA,
    Protein Size: 410
    分子量
    45 kDa
    基因ID
    10002
    NCBI登录号
    NM_014249, NP_055064
    UniProt
    Q9Y5X4
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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