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- 抗原 See all NFATC1 抗体
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NFATC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- PSTSFPVPSK FPLGPAAAVF GRGETLGPAP RAGGTMKSAE EEHYGYASSN
- 预测反应
- Guinea Pig: 86%, Human: 100%, Mouse: 79%, Rat: 86%
- 产品特性
- This is a rabbit polyclonal antibody against NFATC1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NFATC1
- Top Product
- Discover our top product NFATC1 Primary Antibody
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anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (AA 20-300) antibody
NFATC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (AA 601-716) antibodyNFATC1 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (AA 48-406) antibodyNFATC1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (AA 110-210) antibody (PerCP)NFATC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal PerCP
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (AA 110-210) antibody (Atto 594)NFATC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal Atto 594
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (AA 110-210) antibody (Atto 488)NFATC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal Atto 488
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (AA 110-210) antibody (Atto 390)NFATC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal Atto 390
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (C-Term) antibodyNFATC1 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (AA 428-716) antibodyNFATC1 适用: 人 WB, ELISA, FACS, IF, ICC 宿主: 小鼠 Monoclonal AT1C3 unconjugated
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (AA 110-210) antibodyNFATC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 716 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
- 别名
- NFATC1 (NFATC1 产品)
- 别名
- nf-atc antibody, nfat2 antibody, nfatc antibody, si:ch211-198c22.2 antibody, NFATC1 antibody, 2210017P03Rik antibody, AI449492 antibody, AV076380 antibody, NF-ATc antibody, NFAT2 antibody, NFATc antibody, Nfatcb antibody, NF-ATC antibody, NF-ATc1 antibody, NFAT antibody, NFATmac antibody, nuclear factor of activated T-cells 1 antibody, nuclear factor of activated T-cells 1 L homeolog antibody, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 antibody, NFATC1 antibody, nfatc1.L antibody, nfatc1 antibody, Nfatc1 antibody
- 背景
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NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of this protein may regulate inducible expression of different cytokine genes. The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Alias Symbols: MGC138448, NF-ATC, NFAT2, NFATc
Protein Interaction Partner: YWHAQ, OGT, PML, GZF1, FOXP3, HDAC4, PIAS1, SUMO1, UBE2I, RPS6KB1, RPS6KA3, HDAC2, HDAC1, HNRNPA1, TUBA1A, KPNB1, HDAC5, KAT2B, EP300, PARP1, HDAC3, PPP3R1, MAPK14, GNB2L1, PRKCA, SPI1, PIM1, EGR2, EGR1,
Protein Size: 716 - 分子量
- 78 kDa
- 基因ID
- 4772
- NCBI登录号
- NM_172390, NP_765978
- UniProt
- Q2M1S3
- 途径
- RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway
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