NR2C1 抗体 (N-Term)
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- 抗原 See all NR2C1 抗体
- NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠, Pig, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR2C1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- ATIEEIAHQI IEQQMGEIVT EQQTGQKIQI VTALDHNTQG KQFILTNHDG
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
- 产品特性
- This is a rabbit polyclonal antibody against NR2C1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NR2C1
- Top Product
- Discover our top product NR2C1 Primary Antibody
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anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (N-Term) antibody
NR2C1 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (AA 1-240) antibodyNR2C1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (AA 1-240) antibodyNR2C1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) antibodyNR2C1 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (AA 1-467) antibodyNR2C1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (N-Term) antibodyNR2C1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (C-Term) antibodyNR2C1 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠, Pig, 斑马鱼, 猴, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (AA 1-240) antibodyNR2C1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (AA 17-124) antibodyNR2C1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) (AA 432-481) antibodyNR2C1 适用: 人, 小鼠, 兔, Cow, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 467 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
- 别名
- NR2C1 (NR2C1 产品)
- 别名
- TR2 antibody, NR2C1 antibody, dor2 antibody, tr2-11 antibody, xDOR2 antibody, DKFZp468M0512 antibody, si:dkey-183c16.2 antibody, zgc:110672 antibody, 4831444H07Rik antibody, 80.3 antibody, Eenr antibody, Tr2-11 antibody, Tr2 antibody, Psg4 antibody, TR2-11 antibody, PSG9 antibody, nr2c1 antibody, nuclear receptor subfamily 2 group C member 1 antibody, nuclear receptor subfamily 2 group C member 1 S homeolog antibody, nuclear receptor subfamily 2, group C, member 1 antibody, pregnancy specific beta-1-glycoprotein 4 antibody, nuclear receptor subfamily 2 group C member 1 L homeolog antibody, NR2C1 antibody, nr2c1.S antibody, nr2c1 antibody, Nr2c1 antibody, PSG4 antibody, nr2c1.L antibody
- 背景
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The nuclear orphan receptors NR2C1 represses transcription and binds DNA as a homodimer. NR2C1 binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. NR2C1 may function as a negative modulator to suppress androgen receptor function in prostate cancer. NR2C1 may exert an important repressor in regulating ER activity in mammary glands. The nuclear orphan receptors TR2 (NR2C1) and TR4 form a heterodimer that binds to the epsilon and gamma globin promoter DR1 sites This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined.
Alias Symbols: TR2, TR2-11
Protein Interaction Partner: PSPC1, MBD3, SIN3A, RCOR1, KDM1A, POLD3, TRIM28, RBM39, MTA2, MTA1, HDAC3, NR2C2, SMARCA4, SFPQ, RBBP7, RBBP4, NONO, HDAC2, HDAC1, HCFC1, DNMT1, CHD4, NUDT3, UBC, PML, HDAC4, NRIP1, AR, ESR1,
Protein Size: 467 - 分子量
- 51 kDa
- 基因ID
- 7181
- NCBI登录号
- NM_001032287, NP_001027458
- UniProt
- Q15626
- 途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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