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- 抗原 See all RUNX1 抗体
- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RUNX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KMSEALPLGA PDGGPALASK LRSGDRSMVE VLADHPGELV RTDSPNFLCS
- 预测反应
- Cow: 79%, Dog: 79%, Guinea Pig: 79%, Human: 79%, Mouse: 100%, Rabbit: 79%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against Runx1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of MOUSE Runx1
- Top Product
- Discover our top product RUNX1 Primary Antibody
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anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 210-310) antibody
RUNX1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2C10 unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 221-480) antibodyRUNX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 150-250) antibodyRUNX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) antibodyRUNX1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 210-310) antibodyRUNX1 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 3A1 unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (pSer304) antibodyRUNX1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 227-255) antibodyRUNX1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 237-337) antibodyRUNX1 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 6C12A5 unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 200-233), (Middle Region) antibodyRUNX1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1 (RUNX1) (AA 227-255) antibodyRUNX1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB15210 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
- 别名
- Runx1 (RUNX1 产品)
- 别名
- RUNX1 antibody, runx1 antibody, AI462102 antibody, AML1 antibody, Cbfa2 antibody, Pebp2a2 antibody, Pebpa2b antibody, AML1-EVI-1 antibody, AMLCR1 antibody, CBFA2 antibody, EVI-1 antibody, PEBP2aB antibody, runxa antibody, Runx-1 antibody, XAML antibody, Xaml1 antibody, aml antibody, aml-1 antibody, aml1 antibody, aml1-evi-1 antibody, amlcr1 antibody, cbfa2 antibody, evi-1 antibody, pebp2ab antibody, Aml1 antibody, uncharacterized LOC473981 antibody, runt-related transcription factor antibody, runt related transcription factor 1 antibody, runt-related transcription factor 1 antibody, runt related transcription factor 1 L homeolog antibody, LOC473981 antibody, runt antibody, Runx1 antibody, RUNX1 antibody, runx1 antibody, runx1.L antibody
- 背景
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CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. Runx1 is essential for the development of normal hematopoiesis. Isoform 4 shows higher binding activities for target genes and binds TCR-beta-E2 and RAG-1 target site with threefold higher affinity than other isoforms. It is less effective in the context of neutrophil terminal differentiation. Runx1 acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the BLK promoter. It inhibits KAT6B-dependent transcriptional activation .
Alias Symbols: AI462102, AML1, Cbfa2, Pebp2a2, Pebpa2b
Protein Interaction Partner: Kat6a, Ubc, Cbfb, Foxp3, Rbbp4, Gata1, Fli1, Phc1, Cdk6, Cbx3, Bmi1, Pml, Mbd3, Smad2, Prmt1, Hdac2, Hcfc1, Gata2, Hdac1, Wdr5, Mta1, Smarcd1, Pcgf5, Smarcc2, Pold3, Smarce1, Set, Mta2, Ash2l, Tal1, Smarcc1, Smarcb1, Smarca4, Sin3a, Rnf2, Ring1, Cbfa2t3,
Protein Size: 387 - 分子量
- 42 kDa
- 基因ID
- 12394
- NCBI登录号
- NM_009821, NP_033951
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