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ASCL2 抗体 (Middle Region)

ASCL2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779425
发货至: 中国
  • 抗原 See all ASCL2 抗体
    ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))
    抗原表位
    • 15
    • 8
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 44
    • 32
    • 19
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼
    宿主
    • 43
    • 4
    • 1
    克隆类型
    • 43
    • 5
    多克隆
    标记
    • 24
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASCL2 antibody is un-conjugated
    应用范围
    • 31
    • 15
    • 13
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    QALRQHVPHG GASKKLSKVE TLRSAVEYIR ALQRLLAEHD AVRNALAGGL
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 77%, Rat: 100%, Zebrafish: 77%
    产品特性
    This is a rabbit polyclonal antibody against ASCL2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human ASCL2
    Top Product
    Discover our top product ASCL2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 193 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Schwitalla, Fingerle, Cammareri, Nebelsiek, Göktuna, Ziegler, Canli, Heijmans, Huels, Moreaux, Rupec, Gerhard, Schmid, Barker, Clevers, Lang, Neumann, Kirchner, Taketo, van den Brink, Sansom, Arkan et al.: "Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties. ..." in: Cell, Vol. 152, Issue 1-2, pp. 25-38, (2013) (PubMed).

  • 抗原
    ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))
    别名
    ASCL2 (ASCL2 产品)
    别名
    ASH2 antibody, HASH2 antibody, MASH2 antibody, bHLHa45 antibody, ASCL2 antibody, 2410083I15Rik antibody, Mash2 antibody, achaete-scute family bHLH transcription factor 2 antibody, ASCL2 antibody, Ascl2 antibody
    背景
    AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1649 BC028140.1 1-1649 1650-1864 BC057801.1 1286-1500
    Alias Symbols: ASH2, HASH2, MASH2, bHLHa45
    Protein Interaction Partner: EP300, APEX1, CALM3, CALM1, HCFC1, TUBB, KMT2C, NCOA6, TUBA4A, RBBP5,
    Protein Size: 193
    分子量
    20 kDa
    基因ID
    430
    NCBI登录号
    NM_005170, NP_005161
    UniProt
    Q99929
    途径
    Stem Cell Maintenance
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