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STAU1/Staufen 抗体 (N-Term)

STAU1 适用: 人, 大鼠, 马, Cow, 豚鼠, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779109
发货至: 中国
  • 抗原 See all STAU1/Staufen (STAU1) 抗体
    STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))
    抗原表位
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    N-Term
    适用
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    人, 大鼠, 马, Cow, 豚鼠, 犬, 兔
    宿主
    • 61
    • 4
    克隆类型
    • 54
    • 11
    多克隆
    标记
    • 30
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    This STAU1/Staufen antibody is un-conjugated
    应用范围
    • 54
    • 21
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    • 4
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    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    SQVQVQVQNP SAALSGSQIL NKNQSLLSQP LMSIPSTTSS LPSENAGRPI
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against STAU1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human STAU1
    Top Product
    Discover our top product STAU1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 577 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))
    别名
    STAU1 (STAU1 产品)
    别名
    STAU1 antibody, DKFZp459A0124 antibody, CG5753 antibody, Dmel\\CG5753 antibody, Dmstau antibody, STAU antibody, Stau antibody, Stauf antibody, dStau antibody, stau antibody, XStau antibody, XStau1 antibody, Staufen antibody, Staufen1 antibody, MGC145034 antibody, 5830401L18Rik antibody, AW549911 antibody, C85792 antibody, fi67e05 antibody, wu:fi67e05 antibody, zgc:77271 antibody, staufen double-stranded RNA binding protein 1 antibody, staufen antibody, RNA binding protein homolog antibody, staufen (RNA binding protein) homolog 1 (Drosophila) antibody, staufen double-stranded RNA binding protein 1 L homeolog antibody, STAU1 antibody, stau antibody, stau1 antibody, STAUFEN antibody, Stau1 antibody, stau1.L antibody
    背景
    This protein is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are haracterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translationStaufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.
    Alias Symbols: FLJ25010, STAU
    Protein Interaction Partner: LONRF1, GLRX3, ZMAT3, NXT1, SPRTN, MATR3, EIF4A3, NUP155, PRDX6, NPEPPS, DDX23, DDX21, AIFM1, INA, ATP6V0D1, SART1, RPL14, AP3D1, CPNE3, IQGAP1, PABPC4, EIF3D, EIF3B, EIF3A, PRKRA, KHSRP, IRS4, SLC25A11, SMC1A, PABPN1, DDX39B, TUBA1A, MOGS, YWHAZ, XPO1, V
    Protein Size: 577
    分子量
    63 kDa
    基因ID
    6780
    NCBI登录号
    NM_017453, NP_059347
    UniProt
    O95793
    途径
    Asymmetric Protein Localization
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