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SFPQ 抗体 (N-Term)

SFPQ 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2778925
发货至: 中国
  • 抗原 See all SFPQ 抗体
    SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
    抗原表位
    • 8
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 47
    • 22
    • 17
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬
    宿主
    • 45
    • 2
    克隆类型
    • 37
    • 10
    多克隆
    标记
    • 26
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SFPQ antibody is un-conjugated
    应用范围
    • 35
    • 20
    • 12
    • 10
    • 9
    • 8
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    VPGPGPGPKQ GPGPGGPKGG KMPGGPKPGG GPGLSTPGGH PKPPHRGGGE
    预测反应
    Cow: 100%, Dog: 100%, Human: 100%, Mouse: 79%, Rat: 79%
    产品特性
    This is a rabbit polyclonal antibody against SFPQ. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human SFPQ
    Top Product
    Discover our top product SFPQ Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 707 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
    别名
    SFPQ (SFPQ 产品)
    别名
    1110004P21Rik antibody, 2810416M14Rik antibody, 5730453G22Rik antibody, 9030402K04Rik antibody, AU021830 antibody, D4Ertd314e antibody, Gm12940 antibody, OTTMUSG00000009329 antibody, PSF antibody, REP1 antibody, hm:zeh0027 antibody, wu:fa11h12 antibody, wu:fd10f03 antibody, zgc:85935 antibody, POMP100 antibody, splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) antibody, splicing factor proline/glutamine-rich antibody, splicing factor proline and glutamine rich antibody, Sfpq antibody, sfpq antibody, SFPQ antibody
    背景
    SFPQ is DNA- and RNA binding protein. It is essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as an heteromer with NONO. It binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. It interacts with U5 snRNA. It may be involved in a pre-mRNA coupled splicing and polyadenylation process as component of a snRNP-free complex with SNRPA/U1A. SFPQ may be involved in homologous DNA pairing. SFPQ is involved in transcriptional regulation. It binds the DNA sequence 5'-CTGAGTC-3' in the insulin-like growth factor response element (IGFRE) and inhibits IGF-I-stimulated transcriptional activity.
    Alias Symbols: PSF, POMP100
    Protein Interaction Partner: SNRPA, PTBP1, NONO, HDAC2, FUS, HUWE1, UBC, SUMO2, MDM2, STAU1, RPA3, RPA2, RPA1, ERG, ASB18, ASB12, WWOX, ASB3, EED, rev, TIMM23B, APBB1, PIN1, WBP4, TCERG1, GAS7, PRPF40A, PARK2, UBD, CD81, PAN2, RNF43, WHSC1, VCAM1, SMAD5, ITGA4, FN1, CSNK2A1, BTK, DNA
    Protein Size: 707
    分子量
    78 kDa
    基因ID
    6421
    NCBI登录号
    NM_005066, NP_005057
    UniProt
    P23246
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