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AFF3 抗体 (Middle Region)

AFF3 适用: 人, 小鼠, Pig, 兔, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2778345
发货至: 中国
  • 抗原 See all AFF3 抗体
    AFF3 (AF4/FMR2 Family, Member 3 (AFF3))
    抗原表位
    • 3
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, Pig, 兔, 大鼠, 犬
    宿主
    • 8
    克隆类型
    • 8
    多克隆
    标记
    • 8
    This AFF3 antibody is un-conjugated
    应用范围
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    APATKDSESA PPSHTSDTPA EKALPKSKRK RKCDNEDDYR EIKKSQGEKD
    预测反应
    Dog: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 77%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against AFF3. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human AFF3
    Top Product
    Discover our top product AFF3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1226 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • To, Faseruk, Gokgoz, Pinnaduwage, Done, Andrulis: "LAF-4 is aberrantly expressed in human breast cancer." in: International journal of cancer. Journal international du cancer, Vol. 115, Issue 4, pp. 568-74, (2005) (PubMed).

  • 抗原
    AFF3 (AF4/FMR2 Family, Member 3 (AFF3))
    别名
    AFF3 (AFF3 产品)
    别名
    id:ibd5053 antibody, LAF4 antibody, MLLT2-like antibody, 3222402O04Rik antibody, A730046J16 antibody, LAF-4 antibody, Laf4 antibody, AF4/FMR2 family member 3 antibody, AF4/FMR2 family, member 3 antibody, AFF3 antibody, aff3 antibody, Aff3 antibody
    背景
    AFF3 is a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL.This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
    Alias Symbols: LAF4, MLLT2-like
    Protein Interaction Partner: CDK9, MLLT3,
    Protein Size: 1226
    分子量
    133 kDa
    基因ID
    3899
    NCBI登录号
    NM_002285, NP_002276
    UniProt
    P51826
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