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E2F4 抗体 (C-Term)

E2F4 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777218
发货至: 中国
  • 抗原 See all E2F4 抗体
    E2F4 (E2F Transcription Factor 4, P107/p130-Binding (E2F4))
    抗原表位
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 40
    • 20
    • 17
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼
    宿主
    • 35
    • 5
    • 2
    克隆类型
    • 36
    • 6
    多克隆
    标记
    • 36
    • 3
    • 2
    • 1
    This E2F4 antibody is un-conjugated
    应用范围
    • 33
    • 20
    • 12
    • 9
    • 8
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    SSELLEELMS SEVFAPLLRL SPPPGDHDYI YNLDESEGVC DLFDVPVLNL
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against E2F4. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human E2F4
    Top Product
    Discover our top product E2F4 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 413 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    E2F4 (E2F Transcription Factor 4, P107/p130-Binding (E2F4))
    别名
    E2F4 (E2F4 产品)
    别名
    E2F-4 antibody, 2010111M04Rik antibody, AI427446 antibody, E2F4 antibody, e2f-4 antibody, fb72f07 antibody, wu:fb72f07 antibody, wu:fe05f06 antibody, zgc:63815 antibody, E2F transcription factor 4 antibody, E2F transcription factor 4 S homeolog antibody, E2F4 antibody, E2f4 antibody, e2f4.S antibody, e2f4 antibody
    背景
    The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins. It is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It also plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer.
    Alias Symbols: E2F-4
    Protein Interaction Partner: RBL2, TFDP1, RBL1, RB1, XPO1, PCM1, HDAC1, POLR1D, CHMP2A, AP3S2, TRIM28, LIN9, ARID3A, NCOR2, HDAC3, AR, CEBPA, LIN54, LIN37, UBC, ATAD2, SIN3A, ASH2L, HCFC1, TRRAP, KAT2A, ID2, E2F1, KMT2A, ID3, SMAD3, NOLC1, TFDP2, NDN, SMAD2, BRCA1, RYBP, RNF144A, FHL
    Protein Size: 413
    分子量
    44 kDa
    基因ID
    1874
    NCBI登录号
    NM_001950, NP_001941
    UniProt
    Q16254
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
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