电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

UPF3B 抗体 (Middle Region)

UPF3B 适用: 人, 小鼠, 大鼠, 犬, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2776615
发货至: 中国
  • 抗原 See all UPF3B 抗体
    UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
    抗原表位
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 兔, Pig
    宿主
    • 14
    克隆类型
    • 14
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    This UPF3B antibody is un-conjugated
    应用范围
    • 9
    • 5
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    KIDRIPERDK LKDEPKIKVH RFLLQAVNQK NLLKKPEKGD EKELDKREKA
    预测反应
    Dog: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against UPF3B. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human UPF3B
    Top Product
    Discover our top product UPF3B Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 483 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
    别名
    UPF3B (UPF3B 产品)
    别名
    HUPF3B antibody, MRXS14 antibody, RENT3B antibody, UPF3X antibody, 5730594O13Rik antibody, AI317193 antibody, AW541158 antibody, RGD1560264 antibody, UPF3B, regulator of nonsense mediated mRNA decay antibody, UPF3 regulator of nonsense transcripts homolog B (yeast) antibody, UPF3B antibody, Upf3b antibody
    背景
    UPF3B is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The protein is one of two functional homologs to yeast Upf3p. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene.
    Alias Symbols: HUPF3B, MRXS14, RENT3B, UPF3X
    Protein Interaction Partner: NCBP1, CIAO1, STAU1, UBC, UPF1, HECW2, RBM8A, UPF2, SMG1, EIF4A3, WIBG, WBP11, RNPS1, SART1, TOP2A, SNRPA1, NXF1, CAND1, COPS5, CUL5, USP21, EXOSC4, MCRS1, XRN1, TTC19, EIF6, UPF3B, HBB, UPF3A,
    Protein Size: 483
    分子量
    58 kDa
    基因ID
    65109
    NCBI登录号
    NM_080632, NP_542199
    UniProt
    Q9BZI7
You are here:
客服