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PHD1 抗体 (N-Term)

EGLN2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, 斑马鱼, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775992
发货至: 中国
  • 抗原 See all PHD1 (EGLN2) 抗体
    PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
    抗原表位
    • 15
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 57
    • 30
    • 15
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, 斑马鱼, 绵羊
    宿主
    • 68
    • 3
    • 1
    克隆类型
    • 65
    • 7
    多克隆
    标记
    • 28
    • 7
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHD1 antibody is un-conjugated
    应用范围
    • 61
    • 35
    • 16
    • 14
    • 13
    • 9
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB)
    序列
    MCLPSPSKPT SLHPCQAMVA CYPGNGLGYV RHVDNPHGDG RCITCIYYLN
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 86%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against EGLN2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human EGLN2
    Top Product
    Discover our top product EGLN2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 146 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Gilbert, Banek, Bauer, Gingery, Needham: "Exercise training attenuates placental ischemia-induced hypertension and angiogenic imbalance in the rat." in: Hypertension, Vol. 60, Issue 6, pp. 1545-51, (2012) (PubMed).

  • 抗原
    PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
    别名
    EGLN2 (EGLN2 产品)
    背景
    The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. EGLN2 encodes an enzyme responsible for this posttranslational modification. Alternative splicing of EGLN2 results in three transcript variants encoding different isoforms.
    Alias Symbols: EIT6, PHD1, HPH-1, HPH-3, HIFPH1, HIF-PH1
    Protein Interaction Partner: SRPK2, CEP192, IKBKG, FAM46A, EPAS1, A2M, MAGEA11, SIAH2, LPP, WTIP, AJUBA, LIMD1, TRIP6, SPRY2, PRPF19, EGLN3, EGLN2, HIF1A, HIF3A, MOB4, POLR2A,
    Protein Size: 146
    分子量
    16 kDa
    基因ID
    112398
    NCBI登录号
    NM_053046
    UniProt
    Q96KS0
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Cell RedoxHomeostasis
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