NR2F2 抗体 (N-Term)
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- 抗原 See all NR2F2 抗体
- NR2F2 (Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 犬, Pig, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR2F2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- AMVVSTWRDP QDEVPGSQGS QASQAPPVPG PPPGAPHTPQ TPGQGGPAST
- 交叉反应
- 牛, 犬, 小鸡, 人, 小鼠, 大鼠
- 预测反应
- Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%
- 产品特性
- This is a rabbit polyclonal antibody against NR2F2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NR2F2
- Top Product
- Discover our top product NR2F2 Primary Antibody
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- 应用备注
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WB Suggested Anti-NR2F2 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: Human brain.
Optimal working dilutions should be determined experimentally by the investigator. - 说明
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Antigen size: 414 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- NR2F2 (Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2))
- 别名
- NR2F2 (NR2F2 产品)
- 别名
- nr2f2 antibody, MGC52954 antibody, ARP1 antibody, COUPTFB antibody, COUPTFII antibody, NF-E3 antibody, NR2F1 antibody, SVP40 antibody, TFCOUP2 antibody, 2700033K02Rik antibody, 9430015G03Rik antibody, ARP-1 antibody, Aporp1 antibody, COUP-TF2 antibody, COUP-TFII antibody, EAR3 antibody, Tcfcoup2 antibody, Tfcoup2 antibody, fc94g08 antibody, svp40 antibody, svp[40] antibody, wu:fc94g08 antibody, nuclear receptor subfamily 2 group F member 2 L homeolog antibody, Nr2f2 protein antibody, nuclear receptor subfamily 2 group F member 2 antibody, nuclear receptor subfamily 2, group F, member 2 antibody, nr2f2.L antibody, nr2f2 antibody, NR2F2 antibody, Nr2f2 antibody
- 背景
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NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation.
Alias Symbols: ARP1, COUP-TFII, COUPTFB, MGC117452, SVP40, TFCOUP2, NF-E3, NR2F1, COUPTFII
Protein Interaction Partner: NSD1, BCL11A, NR2F2, BIK, SETD7, FAM46A, HIPK3, UBC, TFAP4, Cebpb, SMARCAD1, NR2F6, POU5F1, NR3C1, PHB2, TRIP4, PIAS1, BCL11B, TRIM24, EP300, SQSTM1, HDAC1, NCOR2, MYOD1, LCK,
Protein Size: 414 - 分子量
- 45 kDa
- 基因ID
- 7026
- NCBI登录号
- NM_021005, NP_066285
- UniProt
- P24468
- 途径
- Steroid Hormone Mediated Signaling Pathway
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