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IFNK 抗体 (AA 24-195) (HRP)

IFNK 适用: Cow ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN2754591
发货至: 中国
  • 抗原 See all IFNK products
    IFNK (Interferon, kappa (IFNK))
    抗原表位
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-195
    适用
    • 19
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cow
    宿主
    • 19
    • 5
    • 1
    克隆类型
    • 23
    • 2
    多克隆
    标记
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFNK antibody is conjugated to HRP
    应用范围
    • 13
    • 8
    • 2
    • 2
    • 1
    • 1
    ELISA
    交叉反应
    Cow
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Bovine Interferon tau-1 protein (24-195AA)
    亚型
    IgG
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    IFNK (Interferon, kappa (IFNK))
    别名
    IFNT1 (IFNK 产品)
    别名
    IFNK antibody, IFNT1 antibody, INFE1 antibody, RP11-27J8.1 antibody, interferon kappa antibody, IFNK antibody, Ifnk antibody
    背景

    Background: Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.

    Aliases: IFNT1 antibody, Interferon tau-1 antibody, IFN-tau-1 antibody, Antiluteolysin antibody, Trophoblast antiluteolytic protein antibody, Trophoblast protein 1 antibody, TP-1 antibody, Trophoblastin antibody

    UniProt
    P15696
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