电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Sortilin 1 抗体 (AA 610-754) (HRP)

SORT1 适用: 大鼠 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN2754220
发货至: 中国
  • 抗原 See all Sortilin 1 (SORT1) 抗体
    Sortilin 1 (SORT1)
    抗原表位
    • 16
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 610-754
    适用
    • 40
    • 32
    • 26
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 43
    • 5
    • 2
    克隆类型
    • 45
    • 5
    多克隆
    标记
    • 26
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Sortilin 1 antibody is conjugated to HRP
    应用范围
    • 39
    • 19
    • 17
    • 13
    • 13
    • 13
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA
    交叉反应
    大鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Rat Sortilin protein (610-754AA)
    亚型
    IgG
    Top Product
    Discover our top product SORT1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Sortilin 1 (SORT1)
    别名
    Sort1 (SORT1 产品)
    别名
    SORT1 antibody, 19.m02079 antibody, gp95 antibody, ldlcq6 antibody, sortilin antibody, Gp95 antibody, LDLCQ6 antibody, NT3 antibody, 2900053A11Rik antibody, AI852375 antibody, Ntr3 antibody, Ntsr3 antibody, Nt3 antibody, Nts3 antibody, sort1 antibody, zgc:85953 antibody, sortilin 1 antibody, sortilin antibody, sortilin 1 S homeolog antibody, sortilin 1a antibody, SORT1 antibody, TP01_0016 antibody, BBOV_I002730 antibody, sort1.S antibody, Sort1 antibody, sort1a antibody
    背景

    Background: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.

    Aliases: Sort1 antibody, Sortilin antibody, Glycoprotein 110 antibody, Gp110 antibody, Neurotensin receptor 3 antibody, NTR3 antibody

    UniProt
    O54861
    途径
    Neurotrophin Signaling Pathway
You are here:
客服