(5 references)-
- 抗原 See all TNFRSF8 抗体
- TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNFRSF8 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody Ber-H8 recognizes extracellular part of CD30 (Ki-1 antigen), a 105 kDa single chain glycoprotein expressed on Hodgkin's and Reed-Sternberg cells, it is also found in Burkitt's lymphomas, virus-infected T and B lymphocytes, and on normal B and T lymphocytes after activation (T lymphocytes that produce Th2-type cytokines and on CD4+/CD8+ T lymphocytes that co-express CD45RO and the IL4 receptor).
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 克隆位点
- Ber-H8
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TNFRSF8 Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) (AA 19-379) antibody
TNFRSF8 适用: 人 IHC, WB, IHC (p) 宿主: 小鼠 Monoclonal 18D3 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) antibodyTNFRSF8 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 3B10 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) antibodyTNFRSF8 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) (AA 19-379) antibodyTNFRSF8 适用: 人 FACS, IHC, WB, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 4D1C2 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) (AA 131-230) antibodyTNFRSF8 适用: 人, Pig FACS, WB, IHC (p), ELISA, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) antibodyTNFRSF8 适用: 人 FACS, IHC (p) 宿主: 小鼠 Monoclonal MEM-268 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) antibody (APC)TNFRSF8 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-268 APC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) antibodyTNFRSF8 适用: 人 FACS, WB, IHC (p), IP 宿主: 小鼠 Monoclonal Ber-H2 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) (AA 51-150) antibodyTNFRSF8 适用: 大鼠 IHC (p), ELISA, IF (p), IF (cc), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) antibodyTNFRSF8 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Cord blood CD4+ T cells respond to self heat shock protein 60 (HSP60)." in: PLoS ONE, Vol. 6, Issue 9, pp. e24119, (2011) (PubMed).
: "Increased expression and activation of CD30 induce apoptosis in human blood eosinophils." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 3, pp. 2174-83, (2004) (PubMed).
: "Extremely rapid and intense induction of apoptosis in human eosinophils by anti-CD30 antibody treatment in vitro." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 4, pp. 2186-93, (2004) (PubMed).
: "Characterization of the CD30L binding domain on the human CD30 molecule using anti-CD30 antibodies." in: Hybridoma, Vol. 19, Issue 1, pp. 43-8, (2000) (PubMed).
: "CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy." in: Blood, Vol. 85, Issue 1, pp. 1-14, (1995) (PubMed).
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: "Cord blood CD4+ T cells respond to self heat shock protein 60 (HSP60)." in: PLoS ONE, Vol. 6, Issue 9, pp. e24119, (2011) (PubMed).
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- 抗原
- TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
- 别名
- CD30 (TNFRSF8 产品)
- 别名
- CD30 antibody, D1S166E antibody, Ki-1 antibody, Cd30 antibody, Ki antibody, TNFRSF8 antibody, TNF receptor superfamily member 8 antibody, tumor necrosis factor receptor superfamily, member 8 antibody, TNFRSF8 antibody, Tnfrsf8 antibody
- 背景
- TNF receptor superfamily member 8,CD30 is a type I transmembrane glycoprotein of the TNF receptor superfamily. CD30 was originally identified as a cell surface antigen of Hodgkins and Reed-Sternberg cells using monoclonal antibody Ki-1. The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin's disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin's and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin's lymphomas (including Burkitt's lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that co-express CD45RO and the IL4 receptor. Soluble form of CD30 (sCD30) serves as a marker reflecting Th2 immune response.,Ki-1, TNFRSF8, CD30L receptor, D1S166E
- 基因ID
- 943
- UniProt
- P28908
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