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CYP27A1 抗体

CYP27A1 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272272
发货至: 中国
  • 抗原 See all CYP27A1 抗体
    CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))
    适用
    • 36
    • 32
    • 11
    • 1
    宿主
    • 49
    • 2
    克隆类型
    • 42
    • 9
    多克隆
    标记
    • 20
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP27A1 antibody is un-conjugated
    应用范围
    • 32
    • 14
    • 14
    • 13
    • 9
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of CYP27A1 protein. (region surrounding Glu131)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product CYP27A1 Primary Antibody
  • 应用备注
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • Duan, Fu, Wang, Ni, Zhao: "Cholesterol deregulation induced by chronic corticosterone (CORT) stress in pectoralis major of broiler chickens." in: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, Vol. 176, pp. 59-64, (2014) (PubMed).

    Haag, Stadel, Zhou, Bachem, Möller, Debatin, Fulda: "Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells." in: Gut, Vol. 60, Issue 2, pp. 225-37, (2011) (PubMed).

    Korzekwa, Bah, Kurzynowski, Lukasik, Groblewska, Skarzynski: "Leukotrienes modulate secretion of progesterone and prostaglandins during the estrous cycle and early pregnancy in cattle: an in vivo study." in: Reproduction (Cambridge, England), Vol. 140, Issue 5, pp. 767-76, (2011) (PubMed).

  • 抗原
    CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))
    别名
    CYP27A1 (CYP27A1 产品)
    别名
    CP27 antibody, CTX antibody, CYP27 antibody, Cyp27 antibody, P450C27 antibody, 1300013A03Rik antibody, cytochrome P450 family 27 subfamily A member 1 antibody, cytochrome P450, family 27, subfamily a, polypeptide 1 antibody, cytochrome P450, family 27, subfamily A, polypeptide 1 antibody, sterol 26-hydroxylase, mitochondrial antibody, CYP27A1 antibody, Cyp27a1 antibody, cyp27a1 antibody
    背景
    The immunosuppressant cyclosporin A (CsA) forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity.Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins. Human cyclophilin A (CyPA), an intracellular protein of 165 amino acids, is the target of the CsA and is encoded by a single unique gene conserved from yeast to humans. CyPA is involved in T cell differentiation and proliferation and is highly expressed in brain. CyPA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.Synonyms: 12-alpha-triol 27-hydroxylase, 5-beta-cholestane-3-alpha, 7-alpha, CYP27, Cytochrome P-450C27/25, Cytochrome P450 27, Sterol 26-hydroxylase, Sterol 27-hydroxylase, Vitamin D3-25-hydroxylase
    分子量
    approx. 60 kDa
    基因ID
    1593
    NCBI登录号
    NP_000775
    UniProt
    Q02318
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