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- 抗原 See all CYP27A1 抗体
- CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYP27A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects endogenous levels of CYP27A1 protein. (region surrounding Glu131)
- 交叉反应 (详细)
- Species reactivity (tested):Human.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product CYP27A1 Primary Antibody
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- 应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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Cholesterol deregulation induced by chronic corticosterone (CORT) stress in pectoralis major of broiler chickens." in: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, Vol. 176, pp. 59-64, (2014) (PubMed).
: "Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells." in: Gut, Vol. 60, Issue 2, pp. 225-37, (2011) (PubMed).
: "Leukotrienes modulate secretion of progesterone and prostaglandins during the estrous cycle and early pregnancy in cattle: an in vivo study." in: Reproduction (Cambridge, England), Vol. 140, Issue 5, pp. 767-76, (2011) (PubMed).
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Cholesterol deregulation induced by chronic corticosterone (CORT) stress in pectoralis major of broiler chickens." in: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, Vol. 176, pp. 59-64, (2014) (PubMed).
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- 抗原
- CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))
- 别名
- CYP27A1 (CYP27A1 产品)
- 别名
- CP27 antibody, CTX antibody, CYP27 antibody, Cyp27 antibody, P450C27 antibody, 1300013A03Rik antibody, cytochrome P450 family 27 subfamily A member 1 antibody, cytochrome P450, family 27, subfamily a, polypeptide 1 antibody, cytochrome P450, family 27, subfamily A, polypeptide 1 antibody, sterol 26-hydroxylase, mitochondrial antibody, CYP27A1 antibody, Cyp27a1 antibody, cyp27a1 antibody
- 背景
- The immunosuppressant cyclosporin A (CsA) forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity.Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins. Human cyclophilin A (CyPA), an intracellular protein of 165 amino acids, is the target of the CsA and is encoded by a single unique gene conserved from yeast to humans. CyPA is involved in T cell differentiation and proliferation and is highly expressed in brain. CyPA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.Synonyms: 12-alpha-triol 27-hydroxylase, 5-beta-cholestane-3-alpha, 7-alpha, CYP27, Cytochrome P-450C27/25, Cytochrome P450 27, Sterol 26-hydroxylase, Sterol 27-hydroxylase, Vitamin D3-25-hydroxylase
- 分子量
- approx. 60 kDa
- 基因ID
- 1593
- NCBI登录号
- NP_000775
- UniProt
- Q02318
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