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CDKL2 抗体

CDKL2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272246
发货至: 中国
  • 抗原 See all CDKL2 抗体
    CDKL2 (Cyclin Dependent Kinase Like 2 (CDKL2))
    适用
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    宿主
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    克隆类型
    • 18
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    多克隆
    标记
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    This CDKL2 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of KKIAMRE protein. (region surrounding Leu240)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product CDKL2 Primary Antibody
  • 应用备注
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    CDKL2 (Cyclin Dependent Kinase Like 2 (CDKL2))
    别名
    CDKL2 (CDKL2 产品)
    别名
    KKIAMRE antibody, P56 antibody, CDKL2 antibody, 5330436L21Rik antibody, AI505225 antibody, Kkm antibody, DKFZp459L235 antibody, kkiamre antibody, cyclin dependent kinase like 2 antibody, cyclin-dependent kinase-like 2 (CDC2-related kinase) antibody, cyclin dependent kinase like 2 L homeolog antibody, CDKL2 antibody, Cdkl2 antibody, cdkl2.L antibody
    背景
    The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis, kidney, brain and lung. KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However, unlike other MAP kinases, the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.Synonyms: Cyclin-dependent kinase-like 2, KKIAMRE, Protein kinase p56 KKIAMRE, Serine/threonine-protein kinase KKIAMRE
    分子量
    approx. 56 kDa
    基因ID
    8999
    NCBI登录号
    NP_003939
    UniProt
    Q92772
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