PRKAR2A 抗体
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- 抗原 See all PRKAR2A 抗体
- PRKAR2A (Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRKAR2A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of PKA IIα reg protein. (region surrounding Pro68)
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product PRKAR2A Primary Antibody
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anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A) (AA 1-105) antibody
PRKAR2A 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6A9 unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A) (AA 43-205), (Regulatory Subunit) antibodyPRKAR2A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A) (AA 1-404) antibodyPRKAR2A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A) (N-Term) antibodyPRKAR2A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A) (AA 1-382) antibodyPRKAR2A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A) (Center) antibodyPRKAR2A 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A) (pSer99) antibodyPRKAR2A 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A) antibodyPRKAR2A 适用: 人, 大鼠, 猴, 犬 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal 5F1 unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A) (pSer96) antibodyPRKAR2A 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A) (AA 312-346) antibodyPRKAR2A 适用: 人 WB 宿主: 兔 Polyclonal RB53012 unconjugated
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- 应用备注
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ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- PRKAR2A (Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A))
- 别名
- PRKAR2A (PRKAR2A 产品)
- 别名
- PKR2 antibody, PRKAR2 antibody, prkar2a antibody, zgc:85886 antibody, PRKAR2A antibody, 1110061A24Rik antibody, AI317181 antibody, AI836829 antibody, RII(alpha) antibody, protein kinase cAMP-dependent type II regulatory subunit alpha antibody, protein kinase, cAMP-dependent, regulatory, type II, alpha, B antibody, protein kinase, cAMP-dependent, regulatory, type II, alpha antibody, protein kinase, cAMP dependent regulatory, type II alpha antibody, protein kinase cAMP-dependent type 2 regulatory subunit alpha antibody, PRKAR2A antibody, prkar2ab antibody, Prkar2a antibody
- 背景
- The second messenger cyclic AMP (cAMP) mediates diverse cellular responses to external signals such as proliferation, ion transport, regulation of metabolism and gene transcription by activation of the cAMP-dependent protein kinase (cAPK or PKA). Activation of PKA occurs when cAMP binds to the two regulatory subunits of the tetrameric PKA holoenzyme resulting in release of active catalytic subunits. Three catalytic (C) subunits have been identified, designated Cα, Cβ and Cγ, that each represent specific gene products. Cα and Cβ are closely related (93 % amino acid sequence similarity), where as Cγ displays 83 % and 79 % similarity to Cα and Cβ, respectively. Activation of transcription upon elevation of cAMP levels results from translocation of PKA to the nucleus where it phosphorylates the transcription factor cAMP response element binding protein (CREB) on serine 133 which in turn leads to TFIIB binding to TATA-box-binding protein TBP1, thus linking phospho-CREB to the pol II transcription initiation complex.Synonyms: PKA R2, PKA RII, PKR2, PRKAR2, cAMP-dependent protein kinase type II-alpha regulatory subunit, protein kinase A RII-alpha
- 分子量
- approx. 45 kDa
- 基因ID
- 5576
- NCBI登录号
- NP_004148
- UniProt
- P13861
- 途径
- Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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