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TCR beta 抗体

TCR beta 适用: 小鼠 FACS, IP, WB, IHC (fro), IHC (f), CyTox 宿主: Armenian Hamster Monoclonal H57 unconjugated
产品编号 ABIN2689917
发货至: 中国
  • 抗原 See all TCR beta 抗体
    TCR beta (T Cell Receptor (TCR) beta (TCR beta))
    适用
    • 30
    • 15
    小鼠
    宿主
    • 22
    • 11
    • 8
    • 4
    Armenian Hamster
    克隆类型
    • 34
    • 11
    单克隆
    标记
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    • 1
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    This TCR beta antibody is un-conjugated
    应用范围
    • 34
    • 12
    • 7
    • 6
    • 5
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    • 2
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    • 1
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Cytotoxicity Test (CyTox)
    品牌
    BD Pharmingen™
    产品特性
    The H57-597 antibody reacts with a common epitope of the β chain of the T-cell Receptor (TCR) complex on αβ TCR-expressing thymocytes and peripheral T lymphocytes and NK1.1+ thymocytes and NK-T cells of all mouse strains tested. It does not react with γδTCR-bearing T cells. In the fetal and adult thymus, the TCR βchain may form homodimers or pair with the pre-TCR achain on the surface of immature thymocytes before expression of the TCR achain. Plate-bound or soluble H57-597 antibody activates αβTCR-bearing T cells, and plate-bound mAb can induce apoptotic death. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

    BD Pharmingen™ Purified Hamster Anti-Mouse TCR β Chain - Purified - Clone H57-597 - Isotype Armenian Hamster IgG2, λ1 - Reactivity Ms - 0.5 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    TCR affinity-purified from mouse T-cell hybridoma DO-11.10
    克隆位点
    H57
    亚型
    IgG2 lambda
    Top Product
    Discover our top product TCR beta Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Saint-Ruf, Panigada, Azogui, Debey, von Boehmer, Grassi: "Different initiation of pre-TCR and gammadeltaTCR signalling." in: Nature, Vol. 406, Issue 6795, pp. 524-7, (2000) (PubMed).

    Vicari, Zlotnik: "Mouse NK1.1+ T cells: a new family of T cells." in: Immunology today, Vol. 17, Issue 2, pp. 71-6, (1996) (PubMed).

    Wagner, Hagman, Linsley, Hodsdon, Freed, Newell: "Rescue of thymocytes from glucocorticoid-induced cell death mediated by CD28/CTLA-4 costimulatory interactions with B7-1/B7-2." in: The Journal of experimental medicine, Vol. 184, Issue 5, pp. 1631-8, (1996) (PubMed).

    Atsuta, Nishimura, Nakamura, Emoto, Iwatsuki, Yoshikai: "Diversity of V gamma gene segments rearranged to the J gamma 4 gene in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 2, pp. 676-84, (1995) (PubMed).

    Davenport, Kumar, Bennett: "Rapid rejection of H2k and H2k/b bone marrow cell grafts by CD8+ T cells and NK cells in irradiated mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 8, pp. 3742-9, (1995) (PubMed).

    van der Heyde, Elloso, Chang, Kaplan, Manning, Weidanz: "Gamma delta T cells function in cell-mediated immunity to acute blood-stage Plasmodium chabaudi adami malaria." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 8, pp. 3985-90, (1995) (PubMed).

    Bendelac, Killeen, Littman, Schwartz: "A subset of CD4+ thymocytes selected by MHC class I molecules." in: Science (New York, N.Y.), Vol. 263, Issue 5154, pp. 1774-8, (1994) (PubMed).

    Ohno, Ono, Hirayama, Shimada, Saito: "Preferential usage of the Fc receptor gamma chain in the T cell antigen receptor complex by gamma/delta T cells localized in epithelia." in: The Journal of experimental medicine, Vol. 179, Issue 1, pp. 365-9, (1994) (PubMed).

    Saint-Ruf, Ungewiss, Groettrup, Bruno, Fehling, von Boehmer: "Analysis and expression of a cloned pre-T cell receptor gene." in: Science (New York, N.Y.), Vol. 266, Issue 5188, pp. 1208-12, (1994) (PubMed).

    Groettrup, von Boehmer: "T cell receptor beta chain dimers on immature thymocytes from normal mice." in: European journal of immunology, Vol. 23, Issue 6, pp. 1393-6, (1993) (PubMed).

    Skeen, Ziegler: "Induction of murine peritoneal gamma/delta T cells and their role in resistance to bacterial infection." in: The Journal of experimental medicine, Vol. 178, Issue 3, pp. 971-84, (1993) (PubMed).

    Lefrancois: "Phenotypic complexity of intraepithelial lymphocytes of the small intestine." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 6, pp. 1746-51, (1991) (PubMed).

    Bonneville, Itohara, Krecko, Mombaerts, Ishida, Katsuki, Berns, Farr, Janeway, Tonegawa: "Transgenic mice demonstrate that epithelial homing of gamma/delta T cells is determined by cell lineages independent of T cell receptor specificity." in: The Journal of experimental medicine, Vol. 171, Issue 4, pp. 1015-26, (1990) (PubMed).

    Gascoigne: "Transport and secretion of truncated T cell receptor beta-chain occurs in the absence of association with CD3." in: The Journal of biological chemistry, Vol. 265, Issue 16, pp. 9296-301, (1990) (PubMed).

    Kubo, Born, Kappler, Marrack, Pigeon: "Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 142, Issue 8, pp. 2736-42, (1989) (PubMed).

  • 抗原
    TCR beta (T Cell Receptor (TCR) beta (TCR beta))
    别名
    TCR beta Chain (TCR beta 产品)
    别名
    TCRbeta antibody, Tib antibody, T cell receptor beta chain antibody, Tcrb antibody
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