(6 references)-
- 抗原 See all CD79b (CD79B) 抗体
- CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD79b antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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Immunoglobulin (Ig) antigen receptors are composed of a non-covalently-associated complex of Ig and two other proteins, Igα and Igβ, clustered as CD79a and CD79b, respectively. CD79b is a membrane glycoprotein of 229 residues, with a predicted relative molecular mass of 36-40 kDa. Its expression is restricted to B lineage cells, has been reported to associate with surface IgM receptor, and may be involved in signal transduction. Antibody 3A2-2E7 (also known as SN8) was generated by immunization of cell membrane preparations from B-prolymphocytic leukemia cells. It has similar reactivity characteristics as clone CB3-1 (another CD79b available from BD Biosciences Pharmingen, Cat. No. 555678). Antibodies CD3-1 and 3A2-2E7 reacts with an epitope that is enhanced on certain B-cell leukemias such as prolymphocytic leukemia and lymphoma, but not on chronic lymphocytic leukemia. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of human CD79b expression on peripheral blood lymphocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.
BD Pharmingen™ Purified Mouse Anti-Human CD79b - Purified - Clone 3A2-2E7 (also known as SN8) - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- 3A2
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CD79B Primary Antibody
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anti-CD79b Molecule, Immunoglobulin-Associated beta (CD79B) (AA 29-159) antibody
CD79B 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD79b Molecule, Immunoglobulin-Associated beta (CD79B) antibodyCD79B 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-CD79b Molecule, Immunoglobulin-Associated beta (CD79B) (C-Term) antibodyCD79B 适用: 人 WB, IHC, IF, StM 宿主: 小鼠 Monoclonal B29-123 unconjugated
anti-CD79b Molecule, Immunoglobulin-Associated beta (CD79B) (AA 1-229) antibodyCD79B 适用: 人 WB, IP, ELISA 宿主: 小鼠 Monoclonal 4E10-2A10 unconjugated
anti-CD79b Molecule, Immunoglobulin-Associated beta (CD79B) antibody (FITC)CD79B 适用: 人 FACS 宿主: 小鼠 Monoclonal CB3-1 FITC
anti-CD79b Molecule, Immunoglobulin-Associated beta (CD79B) antibody (PE)CD79B 适用: 人 FACS 宿主: 小鼠 Monoclonal CB3-1 PE
anti-CD79b Molecule, Immunoglobulin-Associated beta (CD79B) (AA 29-229) antibodyCD79B 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-CD79b Molecule, Immunoglobulin-Associated beta (CD79B) antibodyCD79B 适用: 人 FACS, WB, IP, IHC 宿主: 小鼠 Monoclonal CB3-1 unconjugated
anti-CD79b Molecule, Immunoglobulin-Associated beta (CD79B) (AA 182-229) antibodyCD79B 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD79b Molecule, Immunoglobulin-Associated beta (CD79B) (AA 30-160) antibodyCD79B 适用: 人 FACS, WB, IHC, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 4H6A3 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "The alternative transcript of CD79b is overexpressed in B-CLL and inhibits signaling for apoptosis." in: Blood, Vol. 100, Issue 9, pp. 3068-76, (2002) (PubMed).
: "Cross-linking of antigen receptor via Ig-beta (B29, CD79b) can induce both positive and negative signals in CD40-activated human B cells." in: Clinical and experimental immunology, Vol. 110, Issue 3, pp. 509-15, (1998) (PubMed).
: "Improvement of the chronic lymphocytic leukemia scoring system with the monoclonal antibody SN8 (CD79b)." in: American journal of clinical pathology, Vol. 108, Issue 4, pp. 378-82, (1997) (PubMed).
: "Expression of the immunoglobulin-associated protein B29 in B cell disorders with the monoclonal antibody SN8 (CD79b)." in: Leukemia, Vol. 10, Issue 12, pp. 1966-70, (1997) (PubMed).
: "Differential expression of B29 (CD79b) and mb-1 (CD79a) proteins in acute lymphoblastic leukaemia." in: Leukemia, Vol. 10, Issue 5, pp. 769-73, (1996) (PubMed).
: "Three new monoclonal antibodies that define a unique antigen associated with prolymphocytic leukemia/non-Hodgkin's lymphoma and are effectively internalized after binding to the cell surface antigen." in: Blood, Vol. 81, Issue 1, pp. 84-94, (1993) (PubMed).
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: "The alternative transcript of CD79b is overexpressed in B-CLL and inhibits signaling for apoptosis." in: Blood, Vol. 100, Issue 9, pp. 3068-76, (2002) (PubMed).
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- 抗原
- CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
- 别名
- CD79b (CD79B 产品)
- 别名
- B29 antibody, Ig-beta antibody, Igb antibody, Igbeta antibody, AGM6 antibody, IGB antibody, CD79B antigen antibody, CD79b molecule antibody, Cd79b antibody, CD79B antibody
- 背景
- Synonyms: Igβ/SN8/3A2-2E7-1F5
- 途径
- BCR Signaling
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