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CEACAM6 抗体

CEACAM6 适用: 人 FACS 宿主: 小鼠 Monoclonal B6-2-CD66 unconjugated
产品编号 ABIN2689376
发货至: 中国
  • 抗原 See all CEACAM6 抗体
    CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))
    适用
    • 42
    • 2
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    • 1
    宿主
    • 34
    • 8
    小鼠
    克隆类型
    • 34
    • 8
    单克隆
    标记
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    This CEACAM6 antibody is un-conjugated
    应用范围
    • 23
    • 21
    • 10
    • 6
    • 3
    • 2
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    • 1
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    Flow Cytometry (FACS)
    品牌
    BD Pharmingen™
    产品特性
    Reacts with two glycosylphosphatidylinositol-anchored glycoprotein present on granulocytes. Antibody B6.2 was studied as recognizing CD66c in the VI Human Leukocyte Differentiation Antigen workshop. CD66 antigens also known as the carcinoembryonic antigen (CEA) family of molecules, are closely related to the immunoglobulin super family of glycoproteins. Studies on CD66 Molecules suggest a potential adhesion function in vivo. These molecules exhibit both homophilic and heterophilic adhesion. CEA family members may be involved in transmembrane signalling and activation of neutrophils. This clone has been found to be N-terminal domain reactive, reacted preferentially with the native protein and were conformationally dependent. Profile of peripheral blood granulocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.

    BD Pharmingen™ Purified Mouse Anti-Human CD66c - Purified - Clone B6.2/CD66 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    B6-2-CD66
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CEACAM6 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Watt, Teixeira, Zhou, Doyonnas, Zhang, Grunert, Blumberg, Kuroki, Skubitz, Bates: "Homophilic adhesion of human CEACAM1 involves N-terminal domain interactions: structural analysis of the binding site." in: Blood, Vol. 98, Issue 5, pp. 1469-79, (2001) (PubMed).

    Skubitz, Campbell, Ahmed, Skubitz: "CD66 family members are associated with tyrosine kinase activity in human neutrophils." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 11, pp. 5382-90, (1995) (PubMed).

    Kuroki, Arakawa, Matsuo, Oikawa, Misumi, Nakazato, Matsuoka: "Molecular cloning of nonspecific cross-reacting antigens in human granulocytes." in: The Journal of biological chemistry, Vol. 266, Issue 18, pp. 11810-7, (1991) (PubMed).

    Thompson, Grunert, Zimmermann: "Carcinoembryonic antigen gene family: molecular biology and clinical perspectives." in: Journal of clinical laboratory analysis, Vol. 5, Issue 5, pp. 344-66, (1991) (PubMed).

    Szpak, Johnston, Lottich, Kufe, Thor, Schlom: "Patterns of reactivity of four novel monoclonal antibodies (B72.3, DF3, B1.1 and B6.2) with cells in human malignant and benign effusions." in: Acta cytologica, Vol. 28, Issue 4, pp. 356-67, (1984) (PubMed).

  • 抗原
    CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))
    别名
    CD66c (CEACAM6 产品)
    别名
    CD66c antibody, CEAL antibody, NCA antibody, carcinoembryonic antigen-related cell adhesion molecule 6 antibody, carcinoembryonic antigen related cell adhesion molecule 6 antibody, Ceacam6 antibody, CEACAM6 antibody
    背景
    Synonyms: CEA, carcinoembryonic antigen
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