(3 references)-
- 抗原 See all Selectin E/CD62e (SELE) 抗体
- Selectin E/CD62e (SELE) (Selectin E (SELE))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Selectin E/CD62e antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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Reacts with the 97-115 kDa cell surface glycoprotein, E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). E-selectin is thought to be involved in the initial interaction of neutrophils with inflammed endothelium. CD62E is expressed on cytokine-stimulated endothelium, but in minimal amounts on unstimulated endothelium. The adhesion between endothelial E-selectin molecules and a carbohydrate ligand on neutrophils is inhibited by the mAb 68-5H11. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of TNFa-stimulated HUVEC cells analyzed on a FACScan
BD Pharmingen™ Biotin Mouse Anti-Human CD62E - Biotin - Clone 68-5H11 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- 68
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product SELE Primary Antibody
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anti-Selectin E (SELE) (AA 501-612) antibody
SELE 适用: 人, Pig, 小鼠, 大鼠 WB, ELISA, FACS, IHC (fro), IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) (AA 22-230) antibodySELE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) (N-Term) antibodySELE 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) (AA 108-238) antibodySELE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) (AA 260-420) antibodySELE 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) antibodySELE 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) antibodySELE 适用: 小鼠 WB, IHC, ELISA, FACS, IP, IHC (fro), ICC, Func 宿主: 大鼠 Monoclonal UZ5 unconjugated
anti-Selectin E (SELE) antibodySELE 适用: 人 ELISA 宿主: 小鼠 Monoclonal B-P7 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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: "ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex." in: Science (New York, N.Y.), Vol. 250, Issue 4984, pp. 1130-2, (1991) (PubMed).
: "Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins." in: Science (New York, N.Y.), Vol. 243, Issue 4895, pp. 1160-5, (1989) (PubMed).
: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).
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: "ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex." in: Science (New York, N.Y.), Vol. 250, Issue 4984, pp. 1130-2, (1991) (PubMed).
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- 抗原
- Selectin E/CD62e (SELE) (Selectin E (SELE))
- 别名
- CD62E (SELE 产品)
- 别名
- SELE antibody, CD62E antibody, ELAM antibody, ELAM1 antibody, ESEL antibody, LECAM2 antibody, E-selectin antibody, Elam antibody, selectin E antibody, selectin, endothelial cell antibody, SELE antibody, Sele antibody
- 背景
- Synonyms: E-Selectin
- 途径
- Thromboxane A2 Receptor Signaling
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