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MUC1 抗体

MUC1 适用: 人 FACS, IHC (f), IHC (fro) 宿主: 小鼠 Monoclonal HMPV unconjugated
产品编号 ABIN2689100
发货至: 中国
  • 抗原 See all MUC1 抗体
    MUC1 (Mucin 1 (MUC1))
    适用
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    小鼠
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    标记
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    This MUC1 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    品牌
    BD Pharmingen™
    产品特性
    Reacts with the core peptide of the MUC1 protein, a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200 kDa) and an amino acid composition rich in serine, threonin, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats which function as multiple epitopes for the monoclonal antibody. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This antibody has been shown to react with both normal and malignant epithelia of various tissues including breast and colon. Immunohistochemistry of MUC1 positive cells.

    BD Pharmingen™ Purified Mouse Anti-Human CD227 - Purified - Clone HMPV - Isotype Mouse IgG1, κ - Reactivity Hu - 1 mL
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    HMPV
    亚型
    IgG1 kappa
    Top Product
    Discover our top product MUC1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    500 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Devine, Birrell, Whitehead, Harada, Xing, McKenzie: "Expression of MUC1 and MUC2 mucins by human tumor cell lines." in: Tumour biology, Vol. 13, Issue 5-6, pp. 268-77, (1993) (PubMed).

  • 抗原
    MUC1 (Mucin 1 (MUC1))
    别名
    CD227 (MUC1 产品)
    别名
    CA 15-3 antibody, CD227 antibody, EMA antibody, H23AG antibody, KL-6 antibody, MAM6 antibody, MCKD1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1/ZD antibody, PEM antibody, PEMT antibody, PUM antibody, Muc-1 antibody, mucin 1, cell surface associated antibody, mucin 1, transmembrane antibody, MUC1 antibody, Muc1 antibody
    背景
    Synonyms: MUC1
    途径
    Negative Regulation of intrinsic apoptotic Signaling
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