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- 抗原 See all Tissue factor (F3) 抗体
- Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Tissue factor antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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Reacts with a 45-47 kDa, single chain, type I transmembrane protein also known as Tissue Factor (TF). CD142 has been referred in the literature as coagulation Factor III or thromboplastin and it is expressed on activated endothelial cells and lipopolysaccharide (LPS)-stimulated monocytes/macrophages. TF associates with factor VIIa to form a complex and acts as an enzyme that initiates the blood coagulation cascade. It is known as the major initiator of clotting in normal hemostasis. CD142 can be induced by various inflammatory mediators in monocytes and vascular endothelial cells. This antibody is useful in inflammation, thrombosis and hemostasis research. Profile of LPS-stimulated peripheral blood monocytes analyzed by flow cytometry
BD Pharmingen™ Purified Mouse Anti-Human CD142 - Purified - Clone HTF-1 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- HTF
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product F3 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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Fibroblast tissue factor: calcium and ionophore induce shape changes, release of membrane vesicles, and redistribution of tissue factor antigen in addition to increased procoagulant activity." in: Blood, Vol. 84, Issue 2, pp. 526-34, (1994) (PubMed).
: "Tissue factor antigen in senile plaques of Alzheimer's disease." in: The American journal of pathology, Vol. 139, Issue 3, pp. 491-4, (1991) (PubMed).
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Fibroblast tissue factor: calcium and ionophore induce shape changes, release of membrane vesicles, and redistribution of tissue factor antigen in addition to increased procoagulant activity." in: Blood, Vol. 84, Issue 2, pp. 526-34, (1994) (PubMed).
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- 抗原
- Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
- 别名
- CD142 (F3 产品)
- 别名
- CD142 antibody, TF antibody, TFA antibody, PRO1557 antibody, PRO2086 antibody, TFQTL1 antibody, f3 antibody, AA409063 antibody, Cf-3 antibody, Cf3 antibody, tf antibody, zgc:112151 antibody, coagulation factor III, tissue factor antibody, transferrin antibody, coagulation factor IIIa antibody, coagulation factor III antibody, tissue factor antibody, coagulation factor IIIb antibody, coagulation factor III (thromboplastin, tissue factor) S homeolog antibody, F3 antibody, TF antibody, f3a antibody, tf antibody, f3b antibody, f3.S antibody
- 途径
- Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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