STAT5A 抗体 (Signal Transducer and Activator of Transcription 5A) (pTyr694)

Details for Product anti-STAT5A Antibody No. ABIN2687809, 供应商: Log in to see
抗原
  • MGF
  • STAT5
  • AA959963
  • Stat5
  • STAT5A/MGF
  • STATA5
  • STAT5A
  • stat5
  • stat5b
  • stat5a
  • signal transducer and activator of transcription 5A
  • signal transducer and activator of transcription 5a
  • signal transducer and activator of transcription 5B
  • signal transducer and activator of transcription 5B L homeolog
  • STAT5A
  • Stat5a
  • stat5a
  • STAT5B
  • LOC100348518
  • LOC100716811
  • stat5b.L
抗原表位
pTyr694
99
54
50
23
19
16
11
9
9
6
5
5
5
5
5
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠
527
245
216
35
24
19
19
17
7
4
4
1
1
1
1
1
1
宿主

374
157
18
克隆类型
单克隆
标记
This STAT5A antibody is un-conjugated
13
12
11
9
8
8
8
5
4
4
4
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
435
274
182
107
103
103
60
46
26
18
10
9
9
7
6
4
2
2
2
1
1
1
1
1
选项
Supplier
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免疫原 The antiserum was produced against synthesized phosphopeptide derived from human STAT5A around the phosphorylation site of tyrosine 694 (D-G-YP-V-K).
特异性 STAT5A (phospho-Tyr694) antibody detects endogenous levels of STAT5A only when phosphorylated at tyrosine 694.
纯化方法 The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Plasmids, Primers & others Plasmids, Primers & others STAT5A products on genomics-online (e.g. as negative or positive controls)
抗原 Signal Transducer and Activator of Transcription 5A (STAT5A)
别名 STAT5A (STAT5A Antibody 摘要)
背景 This gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
途径 JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
应用备注 WB: 1:500~1:1000 IHC: 1:50~1:100
限制 仅限研究用
状态 Liquid
浓度 1 μg/μL
缓冲液 phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C,-20 °C
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