STAT4 抗体 (Signal Transducer and Activator of Transcription 4) (pTyr693)

Details for Product anti-STAT4 Antibody No. ABIN2687805, 供应商: Log in to see
抗原
  • SLEB11
  • signal transducer and activator of transcription 4
  • STAT4
  • stat4
  • Stat4
抗原表位
pTyr693
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适用
人, 小鼠
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2
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1
宿主

211
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克隆类型
单克隆
标记
This STAT4 antibody is un-conjugated
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11
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4
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1
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
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33
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选项
Supplier
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免疫原 The antiserum was produced against synthesized phosphopeptide derived from human STAT4 around the phosphorylation site of tyrosine 693 (K-G-YP-V-P).
特异性 STAT4 (phospho-Tyr693) antibody detects endogenous levels of STAT4 only when phosphorylated at tyrosine 693.
纯化方法 The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Plasmids, Primers & others Plasmids, Primers & others STAT4 products on genomics-online (e.g. as negative or positive controls)
抗原 Signal Transducer and Activator of Transcription 4 (STAT4)
别名 STAT4 (STAT4 Antibody 摘要)
背景 This gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
途径 JAK/STAT Signaling
应用备注 WB: 1:500~1:1000 IHC: 1:50~1:100
限制 仅限研究用
状态 Liquid
浓度 1 μg/μL
缓冲液 phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C,-20 °C
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