STAT1 抗体 (Signal Transducer and Activator of Transcription 1, 91kDa) (pSer727)

Details for Product anti-STAT1 Antibody No. ABIN2687798, 供应商: Log in to see
抗原
  • CANDF7
  • ISGF-3
  • STAT91
  • 2010005J02Rik
  • AA408197
  • XStat1
  • STAT4
  • DD6G4-4
  • STAT
  • STAT1
  • dZ182H3.3
  • si:by134g18.2
  • si:by51f19.1
  • si:dz182h3.3
  • si:dz199m19.1
  • si:dz73o4.2
  • signal transducer and activator of transcription 1
  • signal transducer and activator of transcription 1 L homeolog
  • signal transducer and activator of transcription 1, 91kDa
  • signal transducer and activator of transcription 4
  • STAT1
  • Stat1
  • stat1.L
  • stat4
抗原表位
pSer727
108
79
55
27
25
21
17
16
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11
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9
8
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6
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5
5
4
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3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠
638
314
260
42
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27
26
23
18
15
11
10
9
5
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3
3
2
2
2
2
1
1
宿主

429
200
19
15
3
1
1
克隆类型
单克隆
标记
This STAT1 antibody is un-conjugated
19
18
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15
13
13
10
7
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5
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4
4
2
2
1
1
1
1
应用范围
Immunohistochemistry (IHC)
552
235
179
120
104
54
52
29
26
12
9
7
5
5
2
1
1
1
选项
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免疫原 The antiserum was produced against synthesized phosphopeptide derived from human STAT1 around the phosphorylation site of serine 727 (P-M-SP-P-E).
特异性 STAT1 (phospho-Ser727) antibody detects endogenous levels of STAT1 only when phosphorylated at serine 727.
纯化方法 The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Plasmids, Primers & others Plasmids, Primers & others STAT1 products on genomics-online (e.g. as negative or positive controls)
抗原 Signal Transducer and Activator of Transcription 1, 91kDa (STAT1)
别名 STAT1 (STAT1 Antibody 摘要)
背景 This gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
途径 JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events
应用备注 IHC: 1:50~1:100
限制 仅限研究用
状态 Liquid
浓度 1 μg/μL
缓冲液 phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C,-20 °C
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