SMAD2 抗体 (SMAD, Mothers Against DPP Homolog 2) (pSer467)

Details for Product anti-SMAD2 Antibody No. ABIN2687786, 供应商: Log in to see
抗原
  • JV18
  • JV18-1
  • MADH2
  • MADR2
  • hMAD-2
  • hSMAD2
  • jv18
  • Xmad2
  • madh2
  • madr2
  • XSmad2
  • hmad-2
  • hsmad2
  • jv18-1
  • smad-2
  • fj43c06
  • wu:fj43c06
  • 7120426M23Rik
  • Madh2
  • Madr2
  • Smad-2
  • mMad2
  • MAD homolog 2
  • Mothers against DPP homolog 2
  • SMAD 2
  • Smad2
  • SMAD family member 2
  • SMAD family member 2-Z
  • SMAD family member 2 S homeolog
  • SMAD2
  • SMAD2Z
  • smad2
  • smad2.S
  • Smad2
抗原表位
pSer467
55
47
29
22
22
19
16
14
13
12
8
7
6
6
6
5
5
5
5
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠
454
266
234
31
23
20
19
19
15
13
11
11
8
7
7
4
2
1
1
1
1
1
1
宿主

392
57
21
克隆类型
多克隆
标记
This SMAD2 antibody is un-conjugated
18
13
12
7
7
7
2
2
2
2
2
2
2
2
2
2
2
2
应用范围
Western Blotting (WB)
408
205
117
90
58
29
28
27
25
24
21
5
5
4
3
3
1
选项
Supplier
Log in to see
Supplier Product No.
Log in to see
免疫原 The antibody was produced against synthesized phosphopeptide derived from human Smad2 around the phosphorylation site of serine 467 (C-S-S-M-SP).
亚型 IgG
特异性 Smad2 (Phospho-Ser467) Antibody detects endogenous levels of Smad2 only when phosphorylated at serine 467.
纯化方法 Affinity purified
Plasmids, Primers & others Plasmids, Primers & others SMAD2 products on genomics-online (e.g. as negative or positive controls)
抗原
别名 SMAD2 (SMAD2 Antibody 摘要)
背景 This gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene ',mothers against decapentaplegic', (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
途径 Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
应用备注 WB: 1:500~1:1000
限制 仅限研究用
状态 Liquid
浓度 1 μg/μL
缓冲液 Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C,-20 °C
您还需要查找其他产品吗?