SMAD, Mothers Against DPP Homolog 1 (SMAD1) (pSer465) 抗体

ABIN2687783 产品详细信息, 供应商: Log in to see
抗原
  • MLP
  • Xmad1
  • Xsmad1
  • bsp1
  • jv4-1
  • jv41
  • madh1
  • madr1
  • smad-1
  • MADH1
  • fb39h09
  • wu:fb39h09
  • wu:fb97e04
  • 2/23
  • CG12399
  • Dmel\\CG12399
  • E(zen)2
  • En(vvl)
  • MAD
  • Mat
  • P-Mad
  • P-mad
  • PMad
  • Smad
  • Smad1
  • apg
  • c28
  • dMAD
  • dMad
  • l(2)K00237
  • l(2)k00237
  • mad
  • p-Mad
  • pMAD
  • pMad
  • pSmad
  • BSP-1
  • BSP1
  • JV4-1
  • JV41
  • MADR1
  • AI528653
  • Madh1
  • Madr1
  • Mlp1
  • MusMLP
  • smad1
  • xmad
  • SMAD family member 1
  • Mothers against dpp
  • SMAD family member 1 L homeolog
  • smad1
  • SMAD1
  • Mad
  • Smad1
  • smad1.L
抗原表位
pSer465
50
35
20
20
18
17
11
10
10
8
7
6
6
5
5
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠
353
233
209
16
16
15
13
11
10
9
8
7
7
6
6
3
2
2
2
2
2
2
2
2
1
宿主

331
48
克隆类型
多克隆
标记
非结合性
15
12
8
3
3
3
3
3
3
3
3
3
3
3
2
2
2
应用范围
Western Blotting (WB)
330
160
110
53
51
39
26
22
16
8
5
4
2
1
1
1
1
1
选项
Supplier
Log in to see
Supplier Product No.
Log in to see
免疫原 The antibody was produced against synthesized phosphopeptide derived from human Smad1 around the phosphorylation site of serine 465 (I-S-S-V-SP).
亚型 IgG
特异性 Smad1 (Phospho-Ser465) Antibody detects endogenous levels of Smad1 only when phosphorylated at serine 465.
纯化方法 Affinity purified
抗原
别名 SMAD1 (SMAD1 Antibody 摘要)
背景 This gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene ',mothers against decapentaplegic', (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
途径 Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
应用备注 WB: 1:500~1:1000
限制 仅限研究用
状态 Liquid
浓度 1 μg/μL
缓冲液 Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C,-20 °C
您还需要查找其他产品吗?