Caspase 6 抗体 (Caspase 6, Apoptosis-Related Cysteine Peptidase)

Details for Product anti-CASP6 Antibody No. ABIN2687737, 供应商: Log in to see
抗原
  • xCaspase-6
  • mch2
  • caspase-6
  • zgc:112960
  • CASP6
  • casp6
  • Mch2
  • mCASP-6
  • MCH2
  • caspase 6 L homeolog
  • caspase 6
  • caspase 6, apoptosis-related cysteine peptidase
  • group XIIA secretory phospholipase A2
  • caspase-6
  • casp6.L
  • casp6
  • CASP6
  • CpipJ_CPIJ017008
  • Casp6
适用
人, 小鼠
293
118
114
18
5
5
5
3
3
1
宿主

284
24
18
克隆类型
单克隆
标记
This Caspase 6 antibody is un-conjugated
20
18
13
9
9
9
3
3
3
3
3
3
3
3
3
3
3
应用范围
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
285
146
145
67
40
36
26
15
13
8
5
5
1
选项
Supplier
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Supplier Product No.
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免疫原 A synthetic peptide corresponding to residues of human Caspase-6 was used as immunogen.
亚型 IgG
特异性 The antibody should recognize the pro-form of Caspase-6 (35 kDa).
纯化方法 Affinity purified
Plasmids, Primers & others Plasmids, Primers & others Caspase 6 products on genomics-online (e.g. as negative or positive controls)
抗原 Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6)
别名 Caspase 6 (CASP6 Antibody 摘要)
背景 Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the initiation and execution of apoptosis. Caspase-6 is a major apoptotic executioner (1,2). It exists as a pro-domain protein and is cleaved by caspase-3 into two active subunits, an 18 kDa and a 10 kDa subunit (3). Caspase-6 cleaves among many different intracellular proteins, nuclear lamins. Lamins play a significant role in maintaining the integrity of the cell membrane, and their cleavage results in subsequent cellular breakdown and death (4).
途径 Apoptosis, Caspase Cascade in Apoptosis
应用备注 WB: 1:1,000, IHC: 1:100, ICC: 1:100, Flow Cytometry: 1:50, IP: 1:50
限制 仅限研究用
状态 Liquid
浓度 1 μg/μL
缓冲液 PBS, pH 7.4 with 0.02 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C,-20 °C
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