PDPK1 抗体 (3-phosphoinositide Dependent Protein Kinase-1) (pSer241)

Details for Product anti-PDPK1 Antibody No. ABIN2687706, 供应商: Log in to see
抗原
  • pdpk1
  • MGC82080
  • PDK1
  • PDPK2
  • PRO0461
  • Pdk1
  • 3'-phosphoinositide-dependent protein kinase 1
  • 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1
  • ATPDK1
  • AtPDK1
  • T32M21.110
  • T32M21_110
  • zgc:77318
  • 3-phosphoinositide dependent protein kinase 1
  • 3-phosphoinositide dependent protein kinase 1 L homeolog
  • 3-phosphoinositide dependent protein kinase-1
  • 3-phosphoinositide-dependent protein kinase 1
  • 3'-phosphoinositide-dependent protein kinase 1
  • 3-phosphoinositide dependent protein kinase 1b
  • PDPK1
  • pdpk1.L
  • pdpk1
  • Pdpk1
  • LOC100380750
  • pdk-1
  • PDK1
  • pdpk1b
抗原表位
pSer241
59
30
28
27
27
17
15
15
15
13
12
8
7
6
6
6
6
5
5
5
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠
446
242
236
21
13
12
11
9
6
5
4
3
2
1
1
1
1
1
1
宿主

389
53
16
克隆类型
单克隆
标记
This PDPK1 antibody is un-conjugated
17
15
14
10
10
7
7
7
7
7
7
7
7
7
5
4
4
3
2
2
2
2
2
2
2
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
306
156
130
91
64
49
28
25
21
11
10
6
3
1
1
选项
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免疫原 The antiserum was produced against synthesized phosphopeptide derived from human PDK1 around the phosphorylation site of serine 241 (A-N-SP-F-V).
特异性 PDK1 (phospho-Ser241) antibody detects endogenous levels of PDK1 only when phosphorylated at serine 241.
纯化方法 The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
Plasmids, Primers & others Plasmids, Primers & others PDPK1 products on genomics-online (e.g. as negative or positive controls)
抗原
别名 PDK1 (PDPK1 Antibody 摘要)
背景 Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
途径 PI3K-Akt Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
应用备注 WB: 1:500~1:1000 IHC: 1:50~1:100
限制 仅限研究用
状态 Liquid
浓度 1 μg/μL
缓冲液 phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C,-20 °C
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