MTOR 抗体 (Mechanistic Target of Rapamycin (serine/threonine Kinase)) (Ser2448)

Details for Product anti-FRAP1 Antibody No. ABIN2687616, 供应商: Log in to see
抗原
  • FRAP1
  • FRAP
  • FRAP2
  • RAFT1
  • RAPT1
  • 2610315D21Rik
  • AI327068
  • Frap1
  • flat
  • frap1
  • tor
  • wu:fc22h08
  • mechanistic target of rapamycin kinase
  • mechanistic target of rapamycin
  • mechanistic target of rapamycin (serine/threonine kinase)
  • MTOR
  • Mtor
  • mtor
抗原表位
Ser2448
68
31
29
22
21
18
16
15
15
11
7
6
6
5
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠
407
221
212
16
8
6
6
6
6
5
4
3
2
1
1
1
宿主

355
49
3
克隆类型
多克隆
标记
This MTOR antibody is un-conjugated
10
10
9
5
4
4
4
4
4
4
4
4
4
4
4
4
4
1
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
294
155
128
69
58
52
33
19
16
8
8
7
3
3
2
2
2
1
1
选项
Supplier
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Supplier Product No.
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免疫原 The antibody was produced against synthesized non-phosphopeptide derived from human mTOR around the phosphorylation site of serine 2448 (T-D-SP-Y-S).
亚型 IgG
特异性 MTOR (Ab-2448) Antibody detects endogenous levels of total mTOR protein.
纯化方法 Affinity purified
Plasmids, Primers & others Plasmids, Primers & others MTOR products on genomics-online (e.g. as negative or positive controls)
抗原
别名 MTOR (FRAP1 Antibody 摘要)
背景 This gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
途径 PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events
应用备注 WB: 1:500~1:1000 IHC: 1:50~1:100 IF:1:100~1:200
限制 仅限研究用
状态 Liquid
浓度 1 μg/μL
缓冲液 Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C,-20 °C
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