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Prelamin A (C-Term), (cleaved), (farnesylated) 抗体

适用: 人 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2669376
发货至: 中国
  • 抗原
    Prelamin A
    抗原表位
    C-Term, cleaved, farnesylated
    适用
    宿主
    • 1
    克隆类型
    • 1
    多克隆
    标记
    • 1
    非结合性
    应用范围
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    特异性
    Anti cleaved farnesylated prelamin A polyclonal antibody detects carboxymethylated prelamin A harbouring the farnesyl residue. This antibody also recognizes progerin, the truncated form of prelamin A found in HutchinsonGilford Progeria Syndrome cells, and does not cross react with mature lamin A.
    产品特性
    The antibody is able to detect cleaved farnesylated prelamin A, while it does not recognize either full-length prelamin A or mature lamin A. This antibody can be used for the discrimination of prelamin A forms and to check the efficacy of potential therapeutic compounds acting on prelamin A processing.
    纯化方法
    Polyclonal immunoglobulins purified by protein A affinity chromatography and stabilized with 5% of glycerol.
    免疫原
    Farnesylated prelamin A C-terminus peptide
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    methanol fixing is suggested

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied in 100 mM sodium citrate, 50 mM Tris and 0.05 % v/v glycerol
    储存条件
    4 °C
  • 抗原
    Prelamin A
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