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IL-22 抗体 (AA 34-179) (PerCP-Cy5.5)

IL22 适用: 小鼠 FACS 宿主: 山羊 Polyclonal Poly5164 PerCP-Cy5.5
产品编号 ABIN2660208
发货至: 中国
  • 抗原 See all IL-22 (IL22) 抗体
    IL-22 (IL22) (Interleukin 22 (IL22))
    抗原表位
    • 16
    • 16
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 34-179
    适用
    • 74
    • 40
    • 26
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 66
    • 12
    • 9
    • 4
    山羊
    克隆类型
    • 69
    • 21
    • 1
    多克隆
    标记
    • 48
    • 15
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-22 antibody is conjugated to PerCP-Cy5.5
    应用范围
    • 73
    • 47
    • 24
    • 13
    • 13
    • 11
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
    免疫原
    AA 34-179 (Accession# NM_016971), was expressed in E. coli.
    克隆位点
    Poly5164
    亚型
    IgG
    Top Product
    Discover our top product IL22 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    IL-22 (IL22) (Interleukin 22 (IL22))
    别名
    IL-22 (IL22 产品)
    别名
    IL-21 antibody, IL-22 antibody, IL-D110 antibody, IL-TIF antibody, ILTIF antibody, TIFIL-23 antibody, TIFa antibody, zcyto18 antibody, IL-22a antibody, ILTIFa antibody, Iltif antibody, RGD1561292 antibody, interleukin-22 antibody, interleukin 22 antibody, IL22 antibody, il22 antibody, Il22 antibody
    背景
    IL-22 is a cytokine structurally related to IL-10. Mouse IL-22 consists of 179 amino acids and has a predicted molecular weight of 20 kD. It is secreted primarily by Th17, Th1, Th2, lymphoid tissue inducer cells (LTi), and subsets of natural killer cells. It has been reported that aryl hydrocarbon receptor (AhR) expression is essential for the production of IL-22 by TCRγδ T cells. AhR activation increases Th17 polarization and induces IL-22 production. IL-22 functions by engaging the heterodimeric IL-22 receptor (IL-22R) complex, consisting of two receptor subunits, IL-22R1 and IL-10Rβ. IL-22 acts on nonhematopoietic tissue cells, such as epithelial cells of the digestive and respiratory systems and keratinocytes of the skin. IL-22 is involved in inflammatory processes such as dermal inflammation, psoriasis, inflammatory bowel disease, hepatitis, and Crohn's disease. Moreover, it plays a critical role in mucosal immunity and the wound healing process.
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