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KLRG1 抗体 (APC)

KLRG1 适用: 小鼠, 人 FACS 宿主: Golden Syrian Hamster Monoclonal 2F1-KLRG1 APC
产品编号 ABIN2658355
发货至: 中国
  • 抗原 See all KLRG1 抗体
    KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
    适用
    • 27
    • 21
    • 1
    小鼠, 人
    宿主
    • 13
    • 11
    • 11
    • 9
    • 1
    Golden Syrian Hamster
    克隆类型
    • 29
    • 16
    单克隆
    标记
    • 19
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This KLRG1 antibody is conjugated to APC
    应用范围
    • 29
    • 13
    • 8
    • 7
    • 2
    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
    克隆位点
    2F1-KLRG1
    亚型
    IgG
    Top Product
    Discover our top product KLRG1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
    别名
    KLRG1 (KLRG1 产品)
    别名
    KLRG1 antibody, 2F1-Ag antibody, MAFA antibody, MAFA-L antibody, 2F1 antibody, CLEC15A antibody, MAFA-2F1 antibody, MAFA-LIKE antibody, killer cell lectin like receptor G1 antibody, killer cell lectin-like receptor subfamily G, member 1 antibody, KLRG1 antibody, Klrg1 antibody
    背景
    Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG1 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.
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