LASS1 抗体
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北京 101111
Quick Overview for LASS1 抗体 (ABIN265221)
抗原
See all LASS1 (CERS1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects Lass1. Detects also GDF1.
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交叉反应 (详细)
- Cross reacts with GDF1
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纯化方法
- Purified
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免疫原
- Synthetic peptide derived from the human Lass1 protein
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亚型
- IgG
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应用备注
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Western Blot (1-5 μg/mL). Positive control: Hypothalamus.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
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- LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))
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别名
- LASS1
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背景
- LAG1 is a longevity gene, the first such gene to be identified. Originally cloned from the yeast Saccharomyces cerevisiae. A close homolog of this gene, LAC1, has been found in the yeast genome. The human homolog of LAG1 has functions in human aging. LAG1 may be involved in neurodegenerative diseases and human aging. Lass1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner. Located in the endoplasmic reticulum membrane, LAss1 is a multi-pass membrane protein.Synonyms: LAG1, LAG1 longevity assurance homolog 1, LASS1, Longevity assurance gene 1 protein homolog 1, UOG1
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基因ID
- 10715
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NCBI登录号
- NP_067090
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UniProt
- P27544
抗原
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