WWTR1 抗体 (WW Domain Containing Transcription Regulator 1)

Details for Product anti-WWTR1 Antibody No. ABIN258561
抗原
  • WWTR1
  • TAZ
  • 2310058J06Rik
  • 2610021I22Rik
  • C78399
  • Taz
  • WW domain containing transcription regulator 1 L homeolog
  • WW domain containing transcription regulator 1
  • wwtr1.L
  • wwtr1
  • WWTR1
  • Wwtr1
适用
人, 小鼠, 大鼠
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9
3
2
1
1
1
宿主

52
14
克隆类型
多克隆
标记
This WWTR1 antibody is un-conjugated
3
2
2
2
2
2
2
2
2
2
2
1
应用范围
Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Simple Western (SimWes), Western Blotting (WB)
52
20
11
6
5
3
2
1
1
选项
免疫原 Synthetic peptides made to the human TAZ protein. These peptides were selected for the lack of homology to YAP protein. [UniProt# Q9GZV5]
纯化方法 Immunogen affinity purified
Plasmids, Primers & others Plasmids, Primers & others WWTR1 products on genomics-online (e.g. as negative or positive controls)
抗原
别名 TAZ/WWTR1 (WWTR1 Antibody 摘要)
背景 Gene Symbol: WWTR1
基因ID 25937
UniProt Q9GZV5
途径 Regulation of Lipid Metabolism by PPARalpha
应用备注 Western Blot 1:1000-1:5000, Simple Western 1:100, Chromatin Immunoprecipitation, Immunocytochemistry/Immunofluorescence 1:50-1:200, Immunoprecipitation 1:100, Immunohistochemistry-ParaffinThis TAZ Antibody is useful for Immunocytochemistry/Immunofluorescence, Immunoprecipitation and Western blot. Use in chromatin immunoprecipitation and Immunohistochemistry-paraffin reported in scientific literature (PMID 25587023). In Simple Western only 10 - 15 μL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue.
说明

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

限制 仅限研究用
状态 Liquid
浓度 1.0 mg/mL
缓冲液 PBS, 15 % glycerol
Buffer contains: 0.02 % Sodium Azide
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid freeze-thaw cycles
储存条件 -80 °C,-20 °C
储存方法 Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
厂商提供的图像
Western Blotting (WB) image for anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibody (ABIN258561) Detection of ABIN258561 protein using ABIN258561 on HEK 293 cell lysate.
Simple Western (SimWes) image for anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibody (ABIN258561) Simple Western: TAZ/WWTR1 Antibody [ABIN2585619] - Simple Western lane view shows a s...
Western Blotting (WB) image for anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibody (ABIN258561) Western Blot: TAZ/WWTR1 Antibody [ABIN2585619] - WB analysis of Taz in HEK293T cell l...
Immunofluorescence (IF) image for anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibody (ABIN258561) Immunocytochemistry/Immunofluorescence: TAZ/WWTR1 Antibody [ABIN2585619] - Detection ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibody (ABIN258561) Immunohistochemistry-Paraffin: TAZ/WWTR1 Antibody - IHC analysis of formalin fixed p...
有引用在: Hwang, Kim, Kim, Il Park, Oh, Moon, Byun, Jeong, Kim, Yaffe, Hwang, Hong: "TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression." in: Nature communications, Vol. 10, Issue 1, pp. 421, 2019 (PubMed). Method employed by authors: Chromatin Immunoprecipitation (ChIP) (Sample species: Mouse (Murine)).

Wu, Deng, Wang, Zhao, Wang, Rao, Xu, Zhou, Choi, Rizvi, Remke, Rubin, Johnson, Carroll, Stemmer-Rachamimov, Wu, Zheng, Xin, Ratner, Lu: "Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis." in: Cancer cell, Vol. 33, Issue 2, pp. 292-308.e7, 2018 (PubMed).

Yu, Huo, Liu, Deng, Szymanski, Li, Luo, Hong, Lin, Wang: "PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ." in: Cell stem cell, Vol. 23, Issue 2, pp. 193-209.e5, 2018 (PubMed).

Deng, Wu, Bai, Zhao, Wang, Wang, Xu, Sakabe, Zhou, Xin, Lu: "A reciprocal regulatory loop between TAZ/YAP and G-protein Gαs regulates Schwann cell proliferation and myelination." in: Nature communications, Vol. 8, pp. 15161, 2017 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Human).

Xiang, Gilkes, Hu, Takano, Luo, Lu, Bullen, Samanta, Liang, Semenza: "Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype." in: Oncotarget, Vol. 5, Issue 24, pp. 12509-27, 2015 (PubMed). (Sample species: Human). Further details: Immunocytochemistry,Western Blotting,Immunohistochemistry (Paraffin-embedded Sections),Immunoprecipitation,Chromatin Immunoprecipitation,Immunofluorescence

Xiang, Gilkes, Hu, Luo, Bullen, Liang, Semenza: "HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells." in: Oncotarget, Vol. 6, Issue 14, pp. 11768-78, 2015 (PubMed). (Sample species: Human). Further details: Western Blotting,Chromatin Immunoprecipitation,Immunoprecipitation

de Cristofaro, Di Palma, Ferraro, Corrado, Lucci, Franco, Fusco, Zannini: "TAZ/WWTR1 is overexpressed in papillary thyroid carcinoma." in: European journal of cancer (Oxford, England : 1990), Vol. 47, Issue 6, pp. 926-33, 2011 (PubMed). (Sample species: Rat (Rattus)). Further details: Western Blotting

Strakova, Reed, Ihnatovych: "Human transcriptional coactivator with PDZ-binding motif (TAZ) is downregulated during decidualization." in: Biology of reproduction, Vol. 82, Issue 6, pp. 1112-8, 2010 (PubMed).

Varelas, Miller, Sopko, Song, Gregorieff, Fellouse, Sakuma, Pawson, Hunziker, McNeill, Wrana, Attisano: "The Hippo pathway regulates Wnt/beta-catenin signaling." in: Developmental cell, Vol. 18, Issue 4, pp. 579-91, 2010 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

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