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GABRA1 抗体 (Cytoplasmic Domain) (Biotin)

GABRA1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S415-24 Biotin
产品编号 ABIN2485763
发货至: 中国
  • 抗原 See all GABRA1 抗体
    GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
    抗原表位
    • 20
    • 20
    • 20
    • 19
    • 15
    • 15
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    • 14
    • 11
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    • 9
    • 5
    • 5
    • 3
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 368-419, Cytoplasmic Domain
    适用
    • 131
    • 107
    • 85
    • 14
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
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    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 101
    • 73
    • 2
    小鼠
    克隆类型
    • 101
    • 75
    单克隆
    标记
    • 54
    • 11
    • 11
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    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 6
    • 3
    • 3
    • 3
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    • 2
    • 2
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    • 2
    This GABRA1 antibody is conjugated to Biotin
    应用范围
    • 166
    • 80
    • 75
    • 69
    • 33
    • 28
    • 26
    • 26
    • 17
    • 12
    • 8
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    Detects ~55 kDa. Does not cross-react with GABA A Receptor Alpha2 or other GABA-A Receptors based on KO validation data.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Protein G Purified
    免疫原
    Fusion protein amino acids 368-419 (last cytoplasmic domain before extracellular C-terminus) of human GABA A Receptor Alpha5.
    克隆位点
    S415-24
    亚型
    IgG1
    Top Product
    Discover our top product GABRA1 Primary Antibody
  • 应用备注
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    说明

    A 1:100 dilution of ABIN2485763 was sufficient for detection of GABA-A R, Alpha5 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Conjugated antibodies should be stored at 4°C
  • 抗原
    GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
    别名
    GABA A Receptor (GABRA1 产品)
    别名
    ECA4 antibody, EJM antibody, EJM5 antibody, zgc:153566 antibody, Gabra-1 antibody, gamma-aminobutyric acid type A receptor alpha1 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 1 antibody, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 antibody, gamma-aminobutyric acid receptor subunit alpha-1 antibody, GABRA1 antibody, Gabra1 antibody, gabra1 antibody, LOC100653509 antibody
    背景
    The GABA A Receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2). Recent research shows their usage in investigating side effects of drugs and the effects of learning and memory. Inverse agonists of the Alpha5 subunit may be useful in the treatment of Alzheimer's Disease (3).
    基因ID
    2558
    NCBI登录号
    NP_000801
    UniProt
    P31644
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