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SERPINH1 抗体 (APC)

SERPINH1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 1C4-1A6 APC
产品编号 ABIN2484371
发货至: 中国
  • 抗原 See all SERPINH1 抗体
    SERPINH1 (Serpin Family H Member 1 (SERPINH1))
    适用
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    宿主
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    小鼠
    克隆类型
    • 61
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    单克隆
    标记
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    This SERPINH1 antibody is conjugated to APC
    应用范围
    • 75
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    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Detects 47 kDa.
    交叉反应
    纯化方法
    Protein G Purified
    免疫原
    Human HSP47, full length
    克隆位点
    1C4-1A6
    亚型
    IgG1 kappa
    Top Product
    Discover our top product SERPINH1 Primary Antibody
  • 应用备注
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    说明

    1 μg/ml of ABIN2484371 was sufficient for detection of HSP47 in 20 μg of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Conjugated antibodies should be stored at 4°C
  • 抗原
    SERPINH1 (Serpin Family H Member 1 (SERPINH1))
    别名
    HSP47 (SERPINH1 产品)
    别名
    AsTP3 antibody, CBP1 antibody, CBP2 antibody, HSP47 antibody, OI10 antibody, PPROM antibody, RA-A47 antibody, SERPINH2 antibody, gp46 antibody, SERPINH1 antibody, DKFZp468B197 antibody, cb216 antibody, hsp antibody, hsp47 antibody, id:ibd5060 antibody, wu:fc56b02 antibody, BERF-1 antibody, Cbp1 antibody, Cbp2 antibody, Hsp47 antibody, J6 antibody, Serpinh2 antibody, colligin antibody, astp3 antibody, cbp1 antibody, cbp2 antibody, pig14 antibody, pprom antibody, ra-a47 antibody, serpinh2 antibody, serpin family H member 1 antibody, serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b antibody, serpin H1 antibody, selenoprotein K antibody, serine (or cysteine) peptidase inhibitor, clade H, member 1 antibody, serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) L homeolog antibody, SERPINH1 antibody, serpinh1b antibody, LOC100009353 antibody, Selenok antibody, Serpinh1 antibody, serpinh1.L antibody
    背景
    HSP47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of HSP47 around fibrotic lesions (1). The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since HSP47 binds a single substrate (2). Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils (3).
    基因ID
    871
    NCBI登录号
    NP_001193943
    UniProt
    P50454
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