Calcineurin A 抗体 (AA 264-283) (Atto 390)
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- 抗原 See all Calcineurin A (CAN) 抗体
- Calcineurin A (CAN)
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抗原表位
- AA 264-283
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Calcineurin A antibody is conjugated to Atto 390
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- Detects ~61 kDa.
- 交叉反应
- 犬, 人, 小鼠, 兔, 大鼠
- 纯化方法
- Peptide Affinity Purified
- 免疫原
- Human Calcineurin A peptide (AA 264-283)
- Top Product
- Discover our top product CAN Primary Antibody
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anti-Calcineurin A (CAN) (AA 15-80) antibody
CAN 适用: 大鼠, 小鼠 WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Calcineurin A (CAN) (AA 264-283) antibodyCAN 适用: 人 WB, IP, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcineurin A (CAN) (AA 264-283) antibody (HRP)CAN 适用: 人 WB, IP, IHC, ICC, IF 宿主: 兔 Polyclonal HRP
anti-Calcineurin A (CAN) (AA 264-283) antibody (FITC)CAN 适用: 人 WB, IP, IHC, ICC, IF 宿主: 兔 Polyclonal FITC
anti-Calcineurin A (CAN) (AA 264-283) antibody (Alkaline Phosphatase (AP))CAN 适用: 人 WB, IP, IHC, ICC, IF 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
anti-Calcineurin A (CAN) (AA 264-283) antibody (Biotin)CAN 适用: 人 WB, IP, IHC, ICC, IF 宿主: 兔 Polyclonal Biotin
anti-Calcineurin A (CAN) (AA 264-283) antibody (PE)CAN 适用: 人 WB, IP, IHC, ICC, IF 宿主: 兔 Polyclonal PE
anti-Calcineurin A (CAN) (AA 264-283) antibody (APC)CAN 适用: 人 WB, IP, IHC, ICC, IF 宿主: 兔 Polyclonal APC
anti-Calcineurin A (CAN) (AA 264-283) antibody (PerCP)CAN 适用: 人 WB, IP, IHC, ICC, IF 宿主: 兔 Polyclonal PerCP
anti-Calcineurin A (CAN) (AA 264-283) antibody (Atto 594)CAN 适用: 人 WB, IP, IHC, ICC, IF 宿主: 兔 Polyclonal Atto 594
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- 应用备注
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- WB (1:1000)
- ICC/IF (1:120)
- IHC (1:100)
- optimal dilutions for assays should be determined by the user.
- 说明
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1 μg/ml of ABIN2481974 was sufficient for detection of Calcineurin A in 20 μg of Heat shock Hela lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- Calcineurin A (CAN)
- 别名
- Calcineurin A (CAN 产品)
- 别名
- Cna antibody, DDBDRAFT_0185021 antibody, DDBDRAFT_0217855 antibody, DDB_0185021 antibody, DDB_0217855 antibody, PPP3CC antibody, CAN A1/PP2B antibody, CG1455 antibody, CNA1 antibody, Can antibody, Cana1 antibody, CnA antibody, CnnA21EF antibody, D14 antibody, DmCanA1-100B antibody, Dmel\\CG1455 antibody, PP2B antibody, PP2B 21EF antibody, PpD14 antibody, canA antibody, pMY4 antibody, calcineurin A antibody, Calcineurin A antibody, CaM-dependent protein phosphatase, catalytic subunit antibody, protein phosphatase 3 catalytic subunit alpha antibody, Calcineurin A1 antibody, protein phosphatase 3 catalytic subunit beta antibody, Cna antibody, NFIA_077970 antibody, ACLA_011200 antibody, PAS_chr3_0414 antibody, canA antibody, PPP3CA antibody, CanA1 antibody, PPP3CB antibody
- 背景
- Calcineurin is a heterodimeric phosphatase protein, also known as calcium-dependent serine-threonine phosphatase. The structure consists of a catalytic subunit alpha, Calcineurin A (57-59KDa) the active site and a Ca2+ binding unit, Calcineurin B (19-20KDa) the regulatory subunit(1). Calcineurin plays a key role in the T-cell response growth and differentiation mechanism, regulating the activation of the Nuclear factor of activated T-cells (NFATc) which are important in the expression of IL-2 genes. Calcineurin has been the target of inhibitors, the novel and structural immune-suppressants antifungal drugs(2). Genetic studies in yeast and fungi established the molecular basis of the inhibition mechanism by cyclosporine A and FK506 (3).
- 基因ID
- 5530
- UniProt
- Q08209
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