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ABCB1 抗体 (AA 262-277)

ABCB1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2469658
发货至: 中国
  • 抗原 See all ABCB1 抗体
    ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
    抗原表位
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 262-277
    适用
    • 66
    • 15
    • 11
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 猴
    宿主
    • 45
    • 25
    克隆类型
    • 43
    • 27
    多克隆
    标记
    • 47
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABCB1 antibody is un-conjugated
    应用范围
    • 36
    • 23
    • 22
    • 18
    • 15
    • 13
    • 10
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    ABCB1 antibody was raised against amino acids 262 - 277 of ABCB1 (Human).
    Top Product
    Discover our top product ABCB1 Primary Antibody
  • 应用备注
    ABCB1 antibody can be used in Western Blot, and immunohistochemistry starting at 2.5 μg/mL.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    As with all antibodies avoid freeze/thaw cycles. Store undiluted.
    储存条件
    4 °C/-20 °C
    储存方法
    Store ABCB1 antibody at 4 °C or -20 °C.
  • 抗原
    ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
    别名
    ABCB1 (ABCB1 产品)
    别名
    ABC20 antibody, CD243 antibody, CLCS antibody, GP170 antibody, MDR1 antibody, P-GP antibody, PGY1 antibody, Abcb1 antibody, Mdr1a antibody, p-gp antibody, xemdr antibody, Mdr1 antibody, Mdr1b antibody, Pgy-1 antibody, Pgy1 antibody, mdr antibody, ABCB1 antibody, PGP1 antibody, ATP binding cassette subfamily B member 1 antibody, ATP binding cassette subfamily B member 1A antibody, ATP binding cassette subfamily B member 1 L homeolog antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 1B antibody, ABCB1 antibody, Abcb1a antibody, abcb1.L antibody, Abcb1b antibody, Abcb1 antibody
    背景
    ATP-Binding Cassette Sub-Family B Member 1 (ABCB1, also named P-glycoprotein) is a plasma membrane-associated multidrug transporter that utilizes the energy of ATP hydrolysis to pump toxic xenobiotics out of cells. Unique features of ABCB1 are its very broad substrate specificity and its basal ATPase activity in the absence of transport substrates. Human ABCB1 plays an important role in absorption, distribution, metabolism, excretion and toxicity of pharmacologically relevant drugs. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anti-cancer drugs. This protein also functions as a transporter across the blood-brain barrier.
    基因ID
    5243
    UniProt
    P08183
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