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ETS2 抗体

ETS2 适用: 人, 小鼠, 大鼠, Drosophila melanogaster WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2463906
发货至: 中国
  • 抗原 See all ETS2 抗体
    ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
    适用
    • 46
    • 9
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Drosophila melanogaster
    宿主
    • 41
    • 6
    克隆类型
    • 44
    • 3
    多克隆
    标记
    • 27
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ETS2 antibody is un-conjugated
    应用范围
    • 35
    • 21
    • 16
    • 15
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ETS2.
    Top Product
    Discover our top product ETS2 Primary Antibody
  • 应用备注
    ETS2 antibody can be used for detection of ETS2 by ELISA at 1:312500. ETS2 antibody can be used for detection of ETS2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store ETS2 antibody at -20 °C.
  • 抗原
    ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
    别名
    ETS2 (ETS2 产品)
    背景
    ETS2 contains an ETS DNA-binding domain and belongs to the ETS family. ETS2 is a target of protein kinase C and upregulates GM-CSF. Ets2 and its targets play essential roles in endothelial cell function. Coexpression of Ets-2 and SRC-1 significantly associated with the rate of recurrence and HER expression in breast cancer. Overexpression of ETS2 is associated with human esophageal squamous cell carcinoma. ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).
    分子量
    53 kDa
    基因ID
    2114
    NCBI登录号
    NP_005230
    UniProt
    P15036
    途径
    EGFR Signaling Pathway, Myometrial Relaxation and Contraction
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