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NFX1 抗体

NFX1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2460119
发货至: 中国
  • 抗原 See all NFX1 抗体
    NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))
    适用
    • 29
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    • 3
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    • 2
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    • 2
    宿主
    • 27
    • 2
    克隆类型
    • 27
    • 2
    多克隆
    标记
    • 15
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This NFX1 antibody is un-conjugated
    应用范围
    • 27
    • 13
    • 13
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFX1.
    Top Product
    Discover our top product NFX1 Primary Antibody
  • 应用备注
    NFX1 antibody can be used for detection of NFX1 by ELISA at 1:312500. NFX1 antibody can be used for detection of NFX1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store NFX1 antibody at -20 °C.
  • 抗原
    NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))
    别名
    NFX1 (NFX1 产品)
    别名
    NFX1 antibody, NFX2 antibody, 1300017N15Rik antibody, 3000003M19Rik antibody, NFX.1 antibody, TEG-42 antibody, Tex42 antibody, nuclear transcription factor, X-box binding 1 antibody, nuclear transcription factor, x-box binding 1 antibody, NFX1 antibody, CpipJ_CPIJ011986 antibody, nfx1 antibody, Nfx1 antibody
    背景
    MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.
    分子量
    124 kDa
    基因ID
    4799
    NCBI登录号
    NP_002495
    UniProt
    Q12986
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