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ATP6V1C1 抗体

ATP6V1C1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2460074
发货至: 中国
  • 抗原 See all ATP6V1C1 抗体
    ATP6V1C1 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1))
    适用
    • 18
    • 13
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 20
    • 1
    克隆类型
    • 21
    多克隆
    标记
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATP6V1C1 antibody is un-conjugated
    应用范围
    • 10
    • 9
    • 3
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATP6V1C1.
    Top Product
    Discover our top product ATP6V1C1 Primary Antibody
  • 应用备注
    ATP6V1C1 antibody can be used for detection of ATP6V1C1 by ELISA at 1:312500. ATP6V1C1 antibody can be used for detection of ATP6V1C1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store ATP6V1C1 antibody at -20 °C.
  • 抗原
    ATP6V1C1 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1))
    别名
    ATP6V1C1 (ATP6V1C1 产品)
    别名
    ATP6C antibody, ATP6D antibody, VATC antibody, Vma5 antibody, 1700025B18Rik antibody, U13839 antibody, vatC antibody, ATPase antibody, atp6v1c1 antibody, si:zc215i13.2 antibody, wu:fd12h05 antibody, atp6v1c1l antibody, zgc:92684 antibody, ATPase H+ transporting V1 subunit C1 antibody, ATPase, H+ transporting, lysosomal V1 subunit C1 antibody, ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 antibody, ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 L homeolog antibody, ATPase, H+ transporting, lysosomal, V1 subunit C1a antibody, ATPase, H+ transporting, lysosomal, V1 subunit C1b antibody, ATP6V1C1 antibody, Atp6v1c1 antibody, atp6v1c1 antibody, atp6v1c1.L antibody, atp6v1c1a antibody, atp6v1c1b antibody
    背景
    ATP6V1C1 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    分子量
    42 kDa
    基因ID
    528
    NCBI登录号
    NP_001686
    UniProt
    P21283
    途径
    Transition Metal Ion Homeostasis, Proton Transport
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