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A1CF 抗体

A1CF 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2458553
发货至: 中国
  • 抗原 See all A1CF 抗体
    A1CF (APOBEC1 Complementation Factor (A1CF))
    适用
    • 28
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    宿主
    • 27
    • 2
    克隆类型
    • 29
    多克隆
    标记
    • 19
    • 2
    • 2
    • 2
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    This A1CF antibody is un-conjugated
    应用范围
    • 26
    • 16
    • 14
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    • 4
    • 2
    • 1
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    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human A1CF.
    Top Product
    Discover our top product A1CF Primary Antibody
  • 应用备注
    A1CF antibody can be used for detection of A1CF by ELISA at 1:1562500. A1CF antibody can be used for detection of A1CF by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store A1CF antibody at -20 °C.
  • 抗原
    A1CF (APOBEC1 Complementation Factor (A1CF))
    别名
    A1CF (A1CF 产品)
    别名
    ACF antibody, ACF64 antibody, ACF65 antibody, APOBEC1CF antibody, ASP antibody, 1810073H04Rik antibody, Acf antibody, A1cft antibody, Apobec-1 antibody, acf antibody, acf64 antibody, acf65 antibody, apobec1cf antibody, asp antibody, A1CF antibody, APOBEC1 complementation factor antibody, apobec1 complementation factor antibody, APOBEC1 complementation factor L homeolog antibody, A1CF antibody, A1cf antibody, a1cf antibody, a1cf.L antibody
    背景
    Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. A1CF has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.
    分子量
    65 kDa
    基因ID
    29974
    NCBI登录号
    NP_620311
    UniProt
    Q9NQ94
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