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IREB2 抗体

IREB2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2458508
发货至: 中国
  • 抗原 See all IREB2 抗体
    IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
    适用
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    宿主
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    克隆类型
    • 46
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    多克隆
    标记
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    This IREB2 antibody is un-conjugated
    应用范围
    • 35
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    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IREB2.
    Top Product
    Discover our top product IREB2 Primary Antibody
  • 应用备注
    IREB2 antibody can be used for detection of IREB2 by ELISA at 1:312500. IREB2 antibody can be used for detection of IREB2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store IREB2 antibody at -20 °C.
  • 抗原
    IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
    别名
    IREB2 (IREB2 产品)
    别名
    IREB2 antibody, im:7153062 antibody, DKFZp468N047 antibody, D9Ertd85e antibody, Irp2 antibody, ACO3 antibody, IRP2 antibody, IRP2AD antibody, IREBP2 antibody, iron responsive element binding protein 2 antibody, iron-responsive element binding protein 2 antibody, iron responsive element binding protein 2 L homeolog antibody, IREB2 antibody, ireb2 antibody, Ireb2 antibody, ireb2.L antibody
    背景
    IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
    分子量
    105 kDa
    基因ID
    3658
    NCBI登录号
    NP_004127
    UniProt
    P48200
    途径
    Transition Metal Ion Homeostasis
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