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Shugoshin 抗体

SGOL1 适用: Schizosaccharomyces pombe WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2452123
发货至: 中国
  • 抗原 See all Shugoshin (SGOL1) 抗体
    Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))
    适用
    • 45
    • 5
    • 5
    • 1
    • 1
    Schizosaccharomyces pombe
    宿主
    • 43
    • 3
    克隆类型
    • 44
    • 2
    多克隆
    标记
    • 25
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Shugoshin antibody is un-conjugated
    应用范围
    • 31
    • 27
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    纯化方法
    Affinity purified
    过滤
    Sterile filtered
    Top Product
    Discover our top product SGOL1 Primary Antibody
  • 应用备注
    1) Western blotting: 1,000 fold dilution
    2) Immunofluoresece staining: 100 fold dilution
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    1 mg/mL BSA, PBS ( pH 7.2), 50 % glycerol
    储存液
    Azide free
    储存条件
    -20 °C
  • Yamagishi, Sakuno, Shimura, Watanabe: "Heterochromatin links to centromeric protection by recruiting shugoshin." in: Nature, Vol. 455, Issue 7210, pp. 251-5, (2008) (PubMed).

    Watanabe, Kitajima: "Shugoshin protects cohesin complexes at centromeres." in: Philosophical transactions of the Royal Society of London. Series B, Biological sciences, Vol. 360, Issue 1455, pp. 515-21, discussion 521, (2005) (PubMed).

    Kitajima, Kawashima, Watanabe: "The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis." in: Nature, Vol. 427, Issue 6974, pp. 510-7, (2004) (PubMed).

  • 抗原
    Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))
    Abstract
    SGOL1 产品
    别名
    sgo1 antibody, NY-BR-85 antibody, SGO antibody, Sgo1 antibody, 3300001M08Rik antibody, C81037 antibody, shugoshin 1 antibody, shugoshin centromeric cohesion 1 antibody, shugoshin 1 L homeolog antibody, Sgo1 antibody, sgo1 antibody, sgo1.L antibody, SGO1 antibody
    背景
    Shugoshin 1 (Sgo1), a meiosis-specific protein, protects centromeric Rec8 from degradation during first meiotic division (meiosis I) in fission yeast Schizosaccharomyces pombe. This protein appears at late prophase of meiosis I and is degraded at anaphase I. Heterochromatin protein Swi6 associates directly with Sgo1. A point mutation of Sgo1 (V242E), which abolishes the interaction with Swi6, impairs the centromeric localization and function of Sgo1. The forced centromeric localization of Sgo1 restores proper meiotic chromosome segregation in swi6 cells. Using this antibody in Western blotting, the band of 37 kD was observed in wild type S. pombe MP111 extract.
    UniProt
    Q9P7A0
    途径
    Maintenance of Protein Location
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